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000048169 084__ $$2WoS$$aChemistry, Analytical
000048169 084__ $$2WoS$$aChemistry, Physical
000048169 1001_ $$0P:(DE-HGF)0$$aOszlanczi, A.$$b0
000048169 245__ $$aEffects of Sulfadiazine on Biological Model Membranes
000048169 260__ $$aDordrecht [u.a.]$$bSpringer Science + Business Media B.V$$c2005
000048169 300__ $$a457 - 462
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000048169 440_0 $$08101$$aJournal of Thermal Analysis and Calorimetry$$v82$$x1388-6150$$y2
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000048169 520__ $$aThe effect of sulfadiazine on dipalmitoylphosphatidylethanolamin-dipalmitoylphosphatidylglycerol-water (DPPE-DPPG/water, 20 mass/ mass%, with 0.2 DPPG/DPPE+DPPG molar ratio) vesicles considered as a model system of the cytoplasmic bacterial membranes was studied using DSC and freeze-fracture methods. The sulfadiazine/ lipid molar ratio was varied from 10(-3) up to 1. It was found that the DPPE-DPPG/water system is drastically affected by the sulfadiazine, but there is no concentration effect in a wide range of sulfadiazine/ lipid molar ratios from 10(-2) up to 2 center dot 10(-1). The DSC and freeze-fracture methods reveal that a homogeneous incorporation of the sulfadiazine molecules occurs in the liquid crystalline phase while in the gel phase separation appears. The different local structures can be classified into two different types: vesicle-like and block-type. Although the surface morphology of the domains of both types shows lamellar arrangement, the blocks are constituted from closely packed long units.
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000048169 65320 $$2Author$$aDPPE-DPPG vesicles
000048169 65320 $$2Author$$aDSC
000048169 65320 $$2Author$$afreeze-fracture
000048169 65320 $$2Author$$aphase separation
000048169 65320 $$2Author$$asulfadiazine
000048169 7001_ $$0P:(DE-HGF)0$$aNovak, Cs.$$b1
000048169 7001_ $$0P:(DE-Juel1)129484$$aKlumpp, E.$$b2$$uFZJ
000048169 773__ $$0PERI:(DE-600)2017304-0$$a10.1007/s10973-005-0917-x$$gVol. 82, p. 457 - 462$$p457 - 462$$q82<457 - 462$$tJournal of Thermal Analysis and Calorimetry$$v82$$x1388-6150$$y2005
000048169 8567_ $$uhttp://dx.doi.org/10.1007/s10973-005-0917-x
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