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000048738 0247_ $$2pmc$$apmc:PMC1366681
000048738 0247_ $$2DOI$$a10.1529/biophysj.105.061374
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000048738 084__ $$2WoS$$aBiophysics
000048738 1001_ $$0P:(DE-HGF)0$$aAtanasov, V.$$b0
000048738 245__ $$aMembrane on a Chip. A functional tethered lipid bilayer membrane on silicon oxide surface
000048738 260__ $$aNew York, NY$$bRockefeller Univ. Press$$c2005
000048738 300__ $$a1780 - 1788
000048738 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
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000048738 440_0 $$0882$$aBiophysical Journal$$v89$$x0006-3495
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000048738 520__ $$aTethered membranes have been proven during recent years to be a powerful and flexible biomimetic platform. We reported in a previous article on the design of a new architecture based on the self-assembly of a thiolipid on ultrasmooth gold substrates, which shows extremely good electrical sealing properties as well as functionality of a bilayer membrane. Here, we describe the synthesis of lipids for a more modular design and the adaptation of the linker part to silane chemistry. We were able to form a functional tethered bilayer lipid membrane with good electrical sealing properties covering a silicon oxide surface. We demonstrate the functional incorporation of the ion carrier valinomycin and of the ion channel gramicidin.
000048738 536__ $$0G:(DE-Juel1)FUEK252$$2G:(DE-HGF)$$aMaterialien, Prozesse und Bauelemente für die  Mikro- und Nanoelektronik$$cI01$$x0
000048738 588__ $$aDataset connected to Web of Science, Pubmed
000048738 650_2 $$2MeSH$$aBiophysics: methods
000048738 650_2 $$2MeSH$$aElectric Impedance
000048738 650_2 $$2MeSH$$aElectrochemistry
000048738 650_2 $$2MeSH$$aGold: chemistry
000048738 650_2 $$2MeSH$$aGramicidin: pharmacology
000048738 650_2 $$2MeSH$$aIon Channels: chemistry
000048738 650_2 $$2MeSH$$aIonophores: pharmacology
000048738 650_2 $$2MeSH$$aIons
000048738 650_2 $$2MeSH$$aLipid Bilayers: chemistry
000048738 650_2 $$2MeSH$$aLipid Bilayers: metabolism
000048738 650_2 $$2MeSH$$aLipids: chemistry
000048738 650_2 $$2MeSH$$aMicroscopy, Atomic Force
000048738 650_2 $$2MeSH$$aModels, Chemical
000048738 650_2 $$2MeSH$$aPhosphatidylcholines: chemistry
000048738 650_2 $$2MeSH$$aPhytol: chemistry
000048738 650_2 $$2MeSH$$aProtein Array Analysis: methods
000048738 650_2 $$2MeSH$$aSilanes: chemistry
000048738 650_2 $$2MeSH$$aSilanes: metabolism
000048738 650_2 $$2MeSH$$aSilicon: chemistry
000048738 650_2 $$2MeSH$$aSilicon Dioxide: chemistry
000048738 650_2 $$2MeSH$$aSpectrophotometry
000048738 650_2 $$2MeSH$$aSubstrate Specificity
000048738 650_2 $$2MeSH$$aTemperature
000048738 650_2 $$2MeSH$$aTime Factors
000048738 650_2 $$2MeSH$$aValinomycin: chemistry
000048738 650_2 $$2MeSH$$aValinomycin: pharmacology
000048738 650_7 $$00$$2NLM Chemicals$$a2,3-di-O-phytanyl-sn-glycerol-1-tetraethylene glycol-(3-chloro-dimethylpropyl-silane) ether lipid
000048738 650_7 $$00$$2NLM Chemicals$$a2,3-di-O-phytanyl-sn-glycerol-1-tetraethylene glycol-(3-trichloropropyl-silane) ether lipid
000048738 650_7 $$00$$2NLM Chemicals$$aIon Channels
000048738 650_7 $$00$$2NLM Chemicals$$aIonophores
000048738 650_7 $$00$$2NLM Chemicals$$aIons
000048738 650_7 $$00$$2NLM Chemicals$$aLipid Bilayers
000048738 650_7 $$00$$2NLM Chemicals$$aLipids
000048738 650_7 $$00$$2NLM Chemicals$$aPhosphatidylcholines
000048738 650_7 $$00$$2NLM Chemicals$$aSilanes
000048738 650_7 $$01405-97-6$$2NLM Chemicals$$aGramicidin
000048738 650_7 $$0150-86-7$$2NLM Chemicals$$aPhytol
000048738 650_7 $$02001-95-8$$2NLM Chemicals$$aValinomycin
000048738 650_7 $$032448-32-1$$2NLM Chemicals$$a1,2-diphytanoylphosphatidylcholine
000048738 650_7 $$07440-21-3$$2NLM Chemicals$$aSilicon
000048738 650_7 $$07440-57-5$$2NLM Chemicals$$aGold
000048738 650_7 $$07631-86-9$$2NLM Chemicals$$aSilicon Dioxide
000048738 650_7 $$2WoSType$$aJ
000048738 7001_ $$0P:(DE-HGF)0$$aKnorr, N.$$b1
000048738 7001_ $$0P:(DE-HGF)0$$aDuran, R. S.$$b2
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000048738 7001_ $$0P:(DE-Juel1)128713$$aOffenhäusser, A.$$b4$$uFZJ
000048738 7001_ $$0P:(DE-HGF)0$$aKnoll, W.$$b5
000048738 7001_ $$0P:(DE-HGF)0$$aKöper, I.$$b6
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000048738 8567_ $$2Pubmed Central$$uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1366681
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