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000049743 084__ $$2WoS$$aMicrobiology
000049743 1001_ $$0P:(DE-HGF)0$$aSchügerl, K.$$b0
000049743 245__ $$aIntegrated bioprocesses
000049743 260__ $$aLondon$$bCurrent Biology Ltd.$$c2005
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000049743 440_0 $$014824$$aCurrent Opinion in Microbiology$$v8$$x1369-5274$$y3
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000049743 520__ $$aIntegrated bioprocesses have been developed to optimise yield and cost-effectiveness of production of low and high molecular weight molecules. Low molecular weight products are removed from the cultivation medium with in situ extraction, in situ adsorption or crystallisation to avoid product inhibition. One-pot processes are being developed to replace two-stage reactions. Recent developments in the integrated purification of high molecular weight products focus mainly on the integration of solid/liquid separation and initial product recovery such as expanded bed adsorption or extraction in aqueous two-phase systems. Additionally, new approaches for a more efficient processing of inclusion bodies have been developed.
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000049743 650_2 $$2MeSH$$aBacteria: metabolism
000049743 650_2 $$2MeSH$$aBiotechnology: methods
000049743 650_2 $$2MeSH$$aIndustrial Microbiology: methods
000049743 650_7 $$2WoSType$$aJ
000049743 7001_ $$0P:(DE-Juel1)VDB21816$$aHubbuch, J.$$b1$$uFZJ
000049743 773__ $$0PERI:(DE-600)2019222-8$$a10.1016/j.mib.2005.01.002$$gVol. 8, p. 294 - 300$$p294 - 300$$q8<294 - 300$$tCurrent opinion in microbiology$$v8$$x1369-5274$$y2005
000049743 8567_ $$uhttp://dx.doi.org/10.1016/j.mib.2005.01.002
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