Journal Article PreJuSER-49743

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Integrated bioprocesses

 ;

2005
Current Biology Ltd. London

Current opinion in microbiology 8, 294 - 300 () [10.1016/j.mib.2005.01.002]

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Abstract: Integrated bioprocesses have been developed to optimise yield and cost-effectiveness of production of low and high molecular weight molecules. Low molecular weight products are removed from the cultivation medium with in situ extraction, in situ adsorption or crystallisation to avoid product inhibition. One-pot processes are being developed to replace two-stage reactions. Recent developments in the integrated purification of high molecular weight products focus mainly on the integration of solid/liquid separation and initial product recovery such as expanded bed adsorption or extraction in aqueous two-phase systems. Additionally, new approaches for a more efficient processing of inclusion bodies have been developed.

Keyword(s): Bacteria: metabolism (MeSH) ; Biotechnology: methods (MeSH) ; Industrial Microbiology: methods (MeSH) ; J

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Note: Record converted from VDB: 12.11.2012

Contributing Institute(s):
  1. Biotechnologie 2 (IBT-2)
Research Program(s):
  1. Biotechnologie (L02)

Appears in the scientific report 2005
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 Record created 2012-11-13, last modified 2019-06-25



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