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@ARTICLE{Schgerl:49743,
      author       = {Schügerl, K. and Hubbuch, J.},
      title        = {{I}ntegrated bioprocesses},
      journal      = {Current opinion in microbiology},
      volume       = {8},
      issn         = {1369-5274},
      address      = {London},
      publisher    = {Current Biology Ltd.},
      reportid     = {PreJuSER-49743},
      pages        = {294 - 300},
      year         = {2005},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {Integrated bioprocesses have been developed to optimise
                      yield and cost-effectiveness of production of low and high
                      molecular weight molecules. Low molecular weight products
                      are removed from the cultivation medium with in situ
                      extraction, in situ adsorption or crystallisation to avoid
                      product inhibition. One-pot processes are being developed to
                      replace two-stage reactions. Recent developments in the
                      integrated purification of high molecular weight products
                      focus mainly on the integration of solid/liquid separation
                      and initial product recovery such as expanded bed adsorption
                      or extraction in aqueous two-phase systems. Additionally,
                      new approaches for a more efficient processing of inclusion
                      bodies have been developed.},
      keywords     = {Bacteria: metabolism / Biotechnology: methods / Industrial
                      Microbiology: methods / J (WoSType)},
      cin          = {IBT-2},
      ddc          = {570},
      cid          = {I:(DE-Juel1)VDB56},
      pnm          = {Biotechnologie},
      pid          = {G:(DE-Juel1)FUEK256},
      shelfmark    = {Microbiology},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:15939352},
      UT           = {WOS:000230098000009},
      doi          = {10.1016/j.mib.2005.01.002},
      url          = {https://juser.fz-juelich.de/record/49743},
}