001     49743
005     20190625112037.0
024 7 _ |2 pmid
|a pmid:15939352
024 7 _ |2 DOI
|a 10.1016/j.mib.2005.01.002
024 7 _ |2 WOS
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037 _ _ |a PreJuSER-49743
041 _ _ |a eng
082 _ _ |a 570
084 _ _ |2 WoS
|a Microbiology
100 1 _ |a Schügerl, K.
|b 0
|0 P:(DE-HGF)0
245 _ _ |a Integrated bioprocesses
260 _ _ |a London
|b Current Biology Ltd.
|c 2005
300 _ _ |a 294 - 300
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
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|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |a Current Opinion in Microbiology
|x 1369-5274
|0 14824
|y 3
|v 8
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a Integrated bioprocesses have been developed to optimise yield and cost-effectiveness of production of low and high molecular weight molecules. Low molecular weight products are removed from the cultivation medium with in situ extraction, in situ adsorption or crystallisation to avoid product inhibition. One-pot processes are being developed to replace two-stage reactions. Recent developments in the integrated purification of high molecular weight products focus mainly on the integration of solid/liquid separation and initial product recovery such as expanded bed adsorption or extraction in aqueous two-phase systems. Additionally, new approaches for a more efficient processing of inclusion bodies have been developed.
536 _ _ |a Biotechnologie
|c L02
|2 G:(DE-HGF)
|0 G:(DE-Juel1)FUEK256
|x 0
588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Bacteria: metabolism
650 _ 2 |2 MeSH
|a Biotechnology: methods
650 _ 2 |2 MeSH
|a Industrial Microbiology: methods
650 _ 7 |a J
|2 WoSType
700 1 _ |a Hubbuch, J.
|b 1
|u FZJ
|0 P:(DE-Juel1)VDB21816
773 _ _ |a 10.1016/j.mib.2005.01.002
|g Vol. 8, p. 294 - 300
|p 294 - 300
|q 8<294 - 300
|0 PERI:(DE-600)2019222-8
|t Current opinion in microbiology
|v 8
|y 2005
|x 1369-5274
856 7 _ |u http://dx.doi.org/10.1016/j.mib.2005.01.002
909 C O |o oai:juser.fz-juelich.de:49743
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913 1 _ |k L02
|v Biotechnologie
|l Biotechnologie
|b Leben
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|x 0
914 1 _ |y 2005
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
920 1 _ |k IBT-2
|l Biotechnologie 2
|g IBT
|z ab 31.10.10 weitergeführt IBG-1
|0 I:(DE-Juel1)VDB56
|x 0
970 _ _ |a VDB:(DE-Juel1)77820
980 _ _ |a VDB
980 _ _ |a ConvertedRecord
980 _ _ |a journal
980 _ _ |a I:(DE-Juel1)IBG-1-20101118
980 _ _ |a UNRESTRICTED
981 _ _ |a I:(DE-Juel1)IBG-1-20101118


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