000005104 001__ 5104
000005104 005__ 20180208201517.0
000005104 0247_ $$2pmid$$apmid:19512925
000005104 0247_ $$2DOI$$a10.1097/WCO.0b013e32832d95db
000005104 0247_ $$2WOS$$aWOS:000268380000001
000005104 037__ $$aPreJuSER-5104
000005104 041__ $$aeng
000005104 082__ $$a610
000005104 084__ $$2WoS$$aClinical Neurology
000005104 084__ $$2WoS$$aNeurosciences
000005104 1001_ $$0P:(DE-Juel1)131714$$aZilles, K.$$b0$$uFZJ
000005104 245__ $$aReceptor mapping: Architecture of the human cerebral cortex
000005104 260__ $$aLondon$$bLippincott Williams & Wilkins$$c2009
000005104 300__ $$a331 - 339
000005104 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
000005104 3367_ $$2DataCite$$aOutput Types/Journal article
000005104 3367_ $$00$$2EndNote$$aJournal Article
000005104 3367_ $$2BibTeX$$aARTICLE
000005104 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000005104 3367_ $$2DRIVER$$aarticle
000005104 440_0 $$012001$$aCurrent Opinion in Neurology$$v22$$x1350-7540$$y4
000005104 500__ $$aThe present study is supported by grants (K.Z., K.A.) from the Human Brain Project/Neuroinformatics Research funded by the National Institute of Biomedical Imaging and Bioengineering, the National Institute of Neurological Disorders and Stroke, and the National Institute of Mental Health and by a grant ('The Human Brain Model') to K.Z. from the Helmholtz Initiative on Systems Biology. Further support by the DFG (AM 118/1-2, K.A.) and the German Ministry for Education and Research (BMBF: BICVV to K.Z., 01GW0623 and 01GW0771 to K.A.) is acknowledged.
000005104 520__ $$aCytoarchitectonical brain mapping is of growing interest as a powerful tool for localization of activated brain regions in functional neuroimaging. Mapping of neurotransmitter receptors can provide novel molecular and functionally relevant information to the available cytoarchitectonical brain maps, because receptors are key molecules of neurotransmission. This review highlights the relation between cytoarchitectonical parcellations and the regionally inhomogeneous distribution of receptors. It will demonstrate the potential of receptor mapping for novel and functionally relevant insights into the regional organization of the human cortex.Mapping of a single receptor type can already reveal borders of functionally and cytoarchitectonically distinct cortical regions. The combined mapping of various receptors in each cortical area (receptor fingerprint) represents the balance between different neurotransmitter systems and often reveals hitherto unknown parcellations. Different brain regions are identified as parts of distinct functional systems.Receptor mapping of the human brain, particularly multireceptor mapping, provides a novel and multimodal view of its anatomical, functional and molecular organization. It reveals organizational principles of the segregation of cortical and subcortical structures. It improves our understanding of the brain's architecture beyond the limits of cytoarchitectonics and serves as a basis for clinical and pharmacological studies of brain diseases.
000005104 536__ $$0G:(DE-Juel1)FUEK409$$2G:(DE-HGF)$$aFunktion und Dysfunktion des Nervensystems$$cP33$$x0
000005104 588__ $$aDataset connected to Web of Science, Pubmed
000005104 65320 $$2Author$$acerebral cortex
000005104 65320 $$2Author$$ahuman brain mapping
000005104 65320 $$2Author$$atransmitter receptors
000005104 650_2 $$2MeSH$$aBrain Mapping: methods
000005104 650_2 $$2MeSH$$aCerebral Cortex: anatomy & histology
000005104 650_2 $$2MeSH$$aCerebral Cortex: physiology
000005104 650_2 $$2MeSH$$aHumans
000005104 650_2 $$2MeSH$$aReceptors, Neurotransmitter: physiology
000005104 650_7 $$00$$2NLM Chemicals$$aReceptors, Neurotransmitter
000005104 650_7 $$2WoSType$$aJ
000005104 7001_ $$0P:(DE-Juel1)131631$$aAmunts, K.$$b1$$uFZJ
000005104 773__ $$0PERI:(DE-600)2026967-5$$a10.1097/WCO.0b013e32832d95db$$gVol. 22, p. 331 - 339$$p331 - 339$$q22<331 - 339$$tCurrent opinion in neurology$$v22$$x1350-7540$$y2009
000005104 8567_ $$uhttp://dx.doi.org/10.1097/WCO.0b013e32832d95db
000005104 909CO $$ooai:juser.fz-juelich.de:5104$$pVDB
000005104 915__ $$0StatID:(DE-HGF)0010$$aJCR/ISI refereed
000005104 9141_ $$y2009
000005104 9131_ $$0G:(DE-Juel1)FUEK409$$aDE-HGF$$bGesundheit$$kP33$$lFunktion und Dysfunktion des Nervensystems$$vFunktion und Dysfunktion des Nervensystems$$x0
000005104 9201_ $$0I:(DE-Juel1)INM-1-20090406$$gINM$$kINM-1$$lStrukturelle und funktionelle Organisation des Gehirns$$x0
000005104 9201_ $$0I:(DE-Juel1)INM-2-20090406$$gINM$$kINM-2$$lMolekulare Organisation des Gehirns$$x1
000005104 9201_ $$0I:(DE-82)080010_20140620$$gJARA$$kJARA-BRAIN$$lJülich-Aachen Research Alliance - Translational Brain Medicine$$x2
000005104 970__ $$aVDB:(DE-Juel1)112525
000005104 980__ $$aVDB
000005104 980__ $$aConvertedRecord
000005104 980__ $$ajournal
000005104 980__ $$aI:(DE-Juel1)INM-1-20090406
000005104 980__ $$aI:(DE-Juel1)INM-2-20090406
000005104 980__ $$aI:(DE-82)080010_20140620
000005104 980__ $$aUNRESTRICTED
000005104 981__ $$aI:(DE-Juel1)INM-2-20090406
000005104 981__ $$aI:(DE-Juel1)VDB1046