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@ARTICLE{Zilles:5104,
      author       = {Zilles, K. and Amunts, K.},
      title        = {{R}eceptor mapping: {A}rchitecture of the human cerebral
                      cortex},
      journal      = {Current opinion in neurology},
      volume       = {22},
      issn         = {1350-7540},
      address      = {London},
      publisher    = {Lippincott Williams $\&$ Wilkins},
      reportid     = {PreJuSER-5104},
      pages        = {331 - 339},
      year         = {2009},
      note         = {The present study is supported by grants (K.Z., K.A.) from
                      the Human Brain Project/Neuroinformatics Research funded by
                      the National Institute of Biomedical Imaging and
                      Bioengineering, the National Institute of Neurological
                      Disorders and Stroke, and the National Institute of Mental
                      Health and by a grant ('The Human Brain Model') to K.Z. from
                      the Helmholtz Initiative on Systems Biology. Further support
                      by the DFG (AM 118/1-2, K.A.) and the German Ministry for
                      Education and Research (BMBF: BICVV to K.Z., 01GW0623 and
                      01GW0771 to K.A.) is acknowledged.},
      abstract     = {Cytoarchitectonical brain mapping is of growing interest as
                      a powerful tool for localization of activated brain regions
                      in functional neuroimaging. Mapping of neurotransmitter
                      receptors can provide novel molecular and functionally
                      relevant information to the available cytoarchitectonical
                      brain maps, because receptors are key molecules of
                      neurotransmission. This review highlights the relation
                      between cytoarchitectonical parcellations and the regionally
                      inhomogeneous distribution of receptors. It will demonstrate
                      the potential of receptor mapping for novel and functionally
                      relevant insights into the regional organization of the
                      human cortex.Mapping of a single receptor type can already
                      reveal borders of functionally and cytoarchitectonically
                      distinct cortical regions. The combined mapping of various
                      receptors in each cortical area (receptor fingerprint)
                      represents the balance between different neurotransmitter
                      systems and often reveals hitherto unknown parcellations.
                      Different brain regions are identified as parts of distinct
                      functional systems.Receptor mapping of the human brain,
                      particularly multireceptor mapping, provides a novel and
                      multimodal view of its anatomical, functional and molecular
                      organization. It reveals organizational principles of the
                      segregation of cortical and subcortical structures. It
                      improves our understanding of the brain's architecture
                      beyond the limits of cytoarchitectonics and serves as a
                      basis for clinical and pharmacological studies of brain
                      diseases.},
      keywords     = {Brain Mapping: methods / Cerebral Cortex: anatomy $\&$
                      histology / Cerebral Cortex: physiology / Humans /
                      Receptors, Neurotransmitter: physiology / Receptors,
                      Neurotransmitter (NLM Chemicals) / J (WoSType)},
      cin          = {INM-1 / INM-2 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406 / I:(DE-Juel1)INM-2-20090406 /
                      $I:(DE-82)080010_20140620$},
      pnm          = {Funktion und Dysfunktion des Nervensystems},
      pid          = {G:(DE-Juel1)FUEK409},
      shelfmark    = {Clinical Neurology / Neurosciences},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:19512925},
      UT           = {WOS:000268380000001},
      doi          = {10.1097/WCO.0b013e32832d95db},
      url          = {https://juser.fz-juelich.de/record/5104},
}