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001     5171
005     20200402205628.0
024 7 _ |2 pmid
|a pmid:19053467
024 7 _ |2 DOI
|a 10.1021/ja807691j
024 7 _ |2 WOS
|a WOS:000263320400014
024 7 _ |2 MLZ
|a doi:10.1021/ja807691j
037 _ _ |a PreJuSER-5171
041 _ _ |a eng
082 _ _ |a 540
084 _ _ |2 WoS
|a Chemistry, Multidisciplinary
100 1 _ |0 P:(DE-Juel1)VDB78506
|a Stadler, A.M.
|b 0
|u FZJ
245 _ _ |a Cytoplasmic Water and Hydration Layer Dynamics in Human Red Blood Cells
260 _ _ |a Washington, DC
|b American Chemical Society
|c 2008
300 _ _ |a 16852 - 16853
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|0 0
|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |0 8502
|a Journal of the American Chemical Society
|v 130
|x 0002-7863
|y 50
500 _ _ |a We thank Franz Dernmel for help with the experiment on IRIS, Aysegul Temiz Artmann and Dariusz Porst for help during sample preparation, and Moeava Tehei and Marion Jasnin for fruitful discussions. This work is based on experiments performed at the neutron sources SINQ FRM II and ISIS. This research project has been supported by the European Commission under the sixth Framework Programme through the Key Action: Strengthening the European Research Area, Research Infrastructures. Contract No: RII3-CT-2003-505925.
520 _ _ |a The dynamics of water in human red blood cells was measured with quasielastic incoherent neutron scattering in the temperature range between 290 and 320 K. Neutron spectrometers with time resolutions of 40, 13, and 7 ps were combined to cover time scales of bulk water dynamics to reduced mobility interfacial water motions. A major fraction of approximately 90% of cell water is characterized by a translational diffusion coefficient similar to bulk water. A minor fraction of approximately 10% of cellular water exhibits reduced dynamics. This slow water fraction was attributed to dynamically bound water on the surface of hemoglobin which accounts for approximately half of the hydration layer.
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|2 G:(DE-HGF)
|a Programm Biosoft
|c N03
|x 0
588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Cytoplasm: chemistry
650 _ 2 |2 MeSH
|a Erythrocytes: chemistry
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Water: chemistry
650 _ 7 |0 7732-18-5
|2 NLM Chemicals
|a Water
650 _ 7 |2 WoSType
|a J
693 _ _ |0 EXP:(DE-MLZ)TOF-TOF-20140101
|1 EXP:(DE-MLZ)FRMII-20140101
|5 EXP:(DE-MLZ)TOF-TOF-20140101
|6 EXP:(DE-MLZ)NL2au-20140101
|a Forschungs-Neutronenquelle Heinz Maier-Leibnitz
|e TOFTOF: Cold neutron time-of-flight spectrometer
|f NL2au
|x 0
700 1 _ |0 P:(DE-HGF)0
|a Embs, J.P.
|b 1
700 1 _ |0 P:(DE-HGF)0
|a Digel, I.
|b 2
700 1 _ |0 P:(DE-HGF)0
|a Artmann, G.M.
|b 3
700 1 _ |0 P:(DE-HGF)0
|a Unruh, T.
|b 4
700 1 _ |0 P:(DE-Juel1)131957
|a Büldt, G.
|b 5
|u FZJ
700 1 _ |0 P:(DE-HGF)0
|a Zaccai, G.
|b 6
773 _ _ |0 PERI:(DE-600)1472210-0
|a 10.1021/ja807691j
|g Vol. 130, p. 16852 - 16853
|n 50
|p 16852 - 16853
|q 130<16852 - 16853
|t Journal of the American Chemical Society
|v 130
|x 0002-7863
|y 2008
856 7 _ |u http://dx.doi.org/10.1021/ja807691j
909 C O |o oai:juser.fz-juelich.de:5171
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914 1 _ |a Nachtrag
|y 2008
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
920 1 _ |0 I:(DE-Juel1)ISB-2-20090406
|d 31.12.2010
|g ISB
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|l Molekulare Biophysik
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