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@ARTICLE{Hamacher:54706,
      author       = {Hamacher, K. and Coenen, H. H.},
      title        = {{N}o-carrier-added nucleophilic 18{F}-labelling in an
                      electrochemical cell exemplified by the routine production
                      of [18{F}]altanserin},
      journal      = {Applied radiation and isotopes},
      volume       = {64},
      issn         = {0969-8043},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {PreJuSER-54706},
      pages        = {989 - 994},
      year         = {2006},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {A new type of electrochemical cell with anodic deposition
                      of no-carrier-added [(18)F]fluoride and variable reaction
                      volume has been developed. The reactor is designed for small
                      reaction volumes and non-thermal drying of [(18)F]fluoride.
                      The implementation of this reactor into a complete remotely
                      controlled synthesis device is described for the routine
                      production of [(18)F]altanserin. A radiochemical yield of
                      $23+/-5\%$ was obtained via cryptate-mediated nucleophilic
                      (18)F-fluorination. Batches of up to 6 GBq
                      [(18)F]altanserin, suitable for human application, with a
                      molar activity of >500 GBq/micromol were obtained within 75
                      min.},
      keywords     = {Chromatography, High Pressure Liquid / Electrochemistry:
                      instrumentation / Fluorine Radioisotopes / Isotope Labeling:
                      methods / Ketanserin: analogs $\&$ derivatives / Ketanserin:
                      chemistry / Ketanserin: isolation $\&$ purification /
                      Fluorine Radioisotopes (NLM Chemicals) / Ketanserin (NLM
                      Chemicals) / altanserin (NLM Chemicals) / J (WoSType)},
      cin          = {INC},
      ddc          = {530},
      cid          = {I:(DE-Juel1)VDB53},
      pnm          = {Funktion und Dysfunktion des Nervensystems},
      pid          = {G:(DE-Juel1)FUEK409},
      shelfmark    = {Chemistry, Inorganic $\&$ Nuclear / Nuclear Science $\&$
                      Technology / Radiology, Nuclear Medicine $\&$ Medical
                      Imaging},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:16829074},
      UT           = {WOS:000240297300004},
      doi          = {10.1016/j.apradiso.2006.03.005},
      url          = {https://juser.fz-juelich.de/record/54706},
}