Journal Article

PreJuSER-5504

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Glucose oxidation and PQQ-dependent dehydrogenases in Gluconobacter oxydans

Hölscher, T. ; Schleyer, U. ; Merfort, M. ; Bringer-Meyer, S.FZJ* ; Görisch, H. ; Sahm, H.

2009
Korean Society for Microbiology and Biotechnology Seoul

This record in other databases:      

Please use a persistent id in citations: doi:10.1159/000142890

Abstract: Gluconobacter oxydans is famous for its rapid and incomplete oxidation of a wide range of sugars and sugar alcohols. The organism is known for its efficient oxidation of D-glucose to D-gluconate, which can be further oxidized to two different keto-D-gluconates, 2-keto-D-gluconate and 5-keto-D-gluconate, as well as 2,5-di-keto-D-gluconate. For this oxidation chain and for further oxidation reactions, G. oxydans possesses a high number of membrane-bound dehydrogenases. In this review, we focus on the dehydrogenases involved in D-glucose oxidation and the products formed during this process. As some of the involved dehydrogenases contain pyrroloquinoline quinone (PQQ) as a cofactor, also PQQ synthesis is reviewed. Finally, we will give an overview of further PQQ-dependent dehydrogenases and discuss their functions in G. oxydans ATCC 621H (DSM 2343).

Keyword(s): Coenzymes: metabolism (MeSH) ; Gluconobacter oxydans: enzymology (MeSH) ; Gluconobacter oxydans: genetics (MeSH) ; Glucose: genetics (MeSH) ; Glucose: metabolism (MeSH) ; Oxidation-Reduction (MeSH) ; Oxidoreductases: metabolism (MeSH) ; PQQ Cofactor: genetics (MeSH) ; PQQ Cofactor: metabolism (MeSH) ; Coenzymes ; Glucose ; PQQ Cofactor ; Oxidoreductases ; J ; Gluconobacter (auto) ; 5-Keto-D-gluconate (auto) ; PQQ-dependent dehydrogenases (auto) ; Glucose oxidation (auto) ; Quinoproteins (auto)

Note: Record converted from VDB: 12.11.2012

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Contributing Institute(s):

1. Biotechnologie 1 (IBT-1)

Research Program(s):

1. Biotechnologie (PBT)

Appears in the scientific report 2009

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