TY  - JOUR
AU  - Raible, M.
AU  - Evstigneev, M.
AU  - Bartels, F. W.
AU  - Eckel, R.
AU  - Nguyen-Duong, M.
AU  - Merkel, R.
AU  - Ros, R.
AU  - Anselmetti, D.
AU  - Reimann, P.
TI  - Theoretical Analysis of Single-Molecule Force Spectroscopy Experiments: Heterogeneity of Chemical Bonds
JO  - Biophysical journal
VL  - 90
SN  - 0006-3495
CY  - New York, NY
PB  - Rockefeller Univ. Press
M1  - PreJuSER-56033
SP  - 3851 - 3864
PY  - 2006
N1  - Record converted from VDB: 12.11.2012
AB  - We show that the standard theoretical framework in single-molecule force spectroscopy has to be extended to consistently describe the experimental findings. The basic amendment is to take into account heterogeneity of the chemical bonds via random variations of the force-dependent dissociation rates. This results in a very good agreement between theory and rupture data from several different experiments.
KW  - Biomechanics: methods
KW  - Microscopy, Atomic Force
KW  - Models, Molecular
KW  - Statistical Distributions
KW  - Thermodynamics
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:16513778
C2  - pmc:PMC1459525
UR  - <Go to ISI:>//WOS:000237481500008
DO  - DOI:10.1529/biophysj.105.077099
UR  - https://juser.fz-juelich.de/record/56033
ER  -