Journal Article

PreJuSER-56033

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Theoretical Analysis of Single-Molecule Force Spectroscopy Experiments: Heterogeneity of Chemical Bonds

Raible, M.FZJ* ; Evstigneev, M.FZJ* ; Bartels, F. W.FZJ* ; Eckel, R.FZJ* ; Nguyen-Duong, M.FZJ* ; Merkel, R.FZJ* ; Ros, R.FZJ* ; Anselmetti, D.FZJ* ; Reimann, P.FZJ*

2006
Rockefeller Univ. Press New York, NY

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Please use a persistent id in citations: doi:10.1529/biophysj.105.077099

Abstract: We show that the standard theoretical framework in single-molecule force spectroscopy has to be extended to consistently describe the experimental findings. The basic amendment is to take into account heterogeneity of the chemical bonds via random variations of the force-dependent dissociation rates. This results in a very good agreement between theory and rupture data from several different experiments.

Keyword(s): Biomechanics: methods (MeSH) ; Microscopy, Atomic Force (MeSH) ; Models, Molecular (MeSH) ; Statistical Distributions (MeSH) ; Thermodynamics (MeSH) ; J

Note: Record converted from VDB: 12.11.2012

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Contributing Institute(s):

1. Biologische Schichten (ISG-4)

Research Program(s):

1. Kondensierte Materie (P54)

Appears in the scientific report 2006
Notes: Nachtrag

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