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| 001 | 57202 | ||
| 005 | 20190625110850.0 | ||
| 024 | 7 | _ | |2 pmid |a pmid:16766177 |
| 024 | 7 | _ | |2 DOI |a 10.1016/j.bios.2006.04.001 |
| 024 | 7 | _ | |2 WOS |a WOS:000243541800027 |
| 024 | 7 | _ | |a altmetric:21817236 |2 altmetric |
| 037 | _ | _ | |a PreJuSER-57202 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 570 |
| 084 | _ | _ | |2 WoS |a Biophysics |
| 084 | _ | _ | |2 WoS |a Biotechnology & Applied Microbiology |
| 084 | _ | _ | |2 WoS |a Chemistry, Analytical |
| 084 | _ | _ | |2 WoS |a Electrochemistry |
| 084 | _ | _ | |2 WoS |a Nanoscience & Nanotechnology |
| 100 | 1 | _ | |a Meyer, M. H. F. |b 0 |0 P:(DE-HGF)0 |
| 245 | _ | _ | |a CRP determination based on a novel magnetic biosensor |
| 260 | _ | _ | |a Amsterdam [u.a.] |b Elsevier Science |c 2007 |
| 300 | _ | _ | |a 973 - 979 |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 440 | _ | 0 | |v 22 |
| 500 | _ | _ | |a Record converted from VDB: 12.11.2012 |
| 520 | _ | _ | |a The c-reactive protein (CRP) is a very significant human blood marker for inflammatory processes and is routinely determined for many clinical purposes. The widespread and well established detection method for this approximately 115 kDa hepatic protein is the high-sensitivity ELISA assay (hsCRP-ELISA) in blood serum. New approaches in medical CRP diagnosis (e.g. for CVD, inflammatory bowel disease) require rapid quantification in native matrices. A novel CRP determination method based on magnetic detection is described and tested for human blood serum, saliva and urine. The detection principle is based on two different anti-CRP antibodies (monoclonal, IgG) for CRP trapment and labelling. The linear detection range of this immunosensor ranged from 25 ng/ml to 2.5 microg/ml and is therefore much more sensitive than typical hsCRP-ELISA-assays. |
| 536 | _ | _ | |a Grundlagen für zukünftige Informationstechnologien |c P42 |2 G:(DE-HGF) |0 G:(DE-Juel1)FUEK412 |x 0 |
| 588 | _ | _ | |a Dataset connected to Web of Science, Pubmed |
| 650 | _ | 2 | |2 MeSH |a Biological Markers: blood |
| 650 | _ | 2 | |2 MeSH |a Biosensing Techniques: instrumentation |
| 650 | _ | 2 | |2 MeSH |a Biosensing Techniques: methods |
| 650 | _ | 2 | |2 MeSH |a Blood Chemical Analysis: instrumentation |
| 650 | _ | 2 | |2 MeSH |a Blood Chemical Analysis: methods |
| 650 | _ | 2 | |2 MeSH |a C-Reactive Protein: analysis |
| 650 | _ | 2 | |2 MeSH |a Equipment Design |
| 650 | _ | 2 | |2 MeSH |a Equipment Failure Analysis |
| 650 | _ | 2 | |2 MeSH |a Humans |
| 650 | _ | 2 | |2 MeSH |a Immunoassay: instrumentation |
| 650 | _ | 2 | |2 MeSH |a Immunoassay: methods |
| 650 | _ | 2 | |2 MeSH |a Immunomagnetic Separation: instrumentation |
| 650 | _ | 2 | |2 MeSH |a Immunomagnetic Separation: methods |
| 650 | _ | 2 | |2 MeSH |a Inflammation: blood |
| 650 | _ | 2 | |2 MeSH |a Inflammation: diagnosis |
| 650 | _ | 2 | |2 MeSH |a Magnetics: diagnostic use |
| 650 | _ | 2 | |2 MeSH |a Magnetics: instrumentation |
| 650 | _ | 2 | |2 MeSH |a Microchemistry: instrumentation |
| 650 | _ | 2 | |2 MeSH |a Microchemistry: methods |
| 650 | _ | 2 | |2 MeSH |a Sensitivity and Specificity |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Biological Markers |
| 650 | _ | 7 | |0 9007-41-4 |2 NLM Chemicals |a C-Reactive Protein |
| 650 | _ | 7 | |a J |2 WoSType |
| 653 | 2 | 0 | |2 Author |a c-reactive protein (CRP) |
| 653 | 2 | 0 | |2 Author |a magnetic detection |
| 653 | 2 | 0 | |2 Author |a immumosensor |
| 653 | 2 | 0 | |2 Author |a inflammation |
| 653 | 2 | 0 | |2 Author |a CVD |
| 653 | 2 | 0 | |2 Author |a IBD |
| 700 | 1 | _ | |a Hartmann, M. |b 1 |0 P:(DE-HGF)0 |
| 700 | 1 | _ | |a Krause, H.-J. |b 2 |u FZJ |0 P:(DE-Juel1)128697 |
| 700 | 1 | _ | |a Blankenstein, G. |b 3 |0 P:(DE-HGF)0 |
| 700 | 1 | _ | |a Müller-Chorus, B. |b 4 |0 P:(DE-HGF)0 |
| 700 | 1 | _ | |a Oster, J. |b 5 |0 P:(DE-HGF)0 |
| 700 | 1 | _ | |a Miethe, P. |b 6 |0 P:(DE-HGF)0 |
| 700 | 1 | _ | |a Keusgen, M. |b 7 |u FZJ |0 P:(DE-Juel1)VDB15243 |
| 773 | _ | _ | |a 10.1016/j.bios.2006.04.001 |g Vol. 22, p. 973 - 979 |p 973 - 979 |q 22<973 - 979 |0 PERI:(DE-600)1496379-6 |t Biosensors and bioelectronics |v 22 |y 2007 |x 0956-5663 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1016/j.bios.2006.04.001 |
| 909 | C | O | |o oai:juser.fz-juelich.de:57202 |p VDB |
| 913 | 1 | _ | |k P42 |v Grundlagen für zukünftige Informationstechnologien |l Grundlagen für zukünftige Informationstechnologien (FIT) |b Schlüsseltechnologien |0 G:(DE-Juel1)FUEK412 |x 0 |
| 914 | 1 | _ | |y 2007 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0010 |a JCR/ISI refereed |
| 920 | 1 | _ | |k CNI |l Center of Nanoelectronic Systems for Information Technology |d 14.09.2008 |g CNI |z 381 |0 I:(DE-Juel1)VDB381 |x 1 |
| 920 | 1 | _ | |k IBN-2 |l Bioelektronik |d 31.12.2010 |g IBN |0 I:(DE-Juel1)IBN-2-20090406 |x 0 |
| 970 | _ | _ | |a VDB:(DE-Juel1)89978 |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a ConvertedRecord |
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| 980 | _ | _ | |a I:(DE-Juel1)IBN-2-20090406 |
| 980 | _ | _ | |a UNRESTRICTED |
| 981 | _ | _ | |a I:(DE-Juel1)IBN-2-20090406 |
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