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041 _ _ |a eng
082 _ _ |a 540
084 _ _ |2 WoS
|a Biochemistry & Molecular Biology
100 1 _ |a Nagel, K. A.
|b 0
|u FZJ
|0 P:(DE-Juel1)129373
245 _ _ |a Novel Detection System for Plant Protein Production of Pharmaceuticals and Impact on Conformational Diseases
260 _ _ |a Schiphol
|b Bentham Science Publ.
|c 2010
300 _ _ |a 723 - 731
336 7 _ |a Journal Article
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336 7 _ |a article
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440 _ 0 |a Protein and Peptide Letters
|x 0929-8665
|0 15161
|y 6
|v 17
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a State-of-the-art biochemistry methods in combination with an automated phenotyping method demonstrate the high potential of transgenic tobacco plants in producing properly-folded therapeutic proteins for the treatment of protein-misfolding diseases (e.g., Alzheimer's disease). This molecular farming approach led to highest protein production of hydroponically-grown tobacco compared to other growth substrates generally used in plant cultivation.
536 _ _ |a Terrestrische Umwelt
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588 _ _ |a Dataset connected to Web of Science
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653 2 0 |2 Author
|a Protein folding
653 2 0 |2 Author
|a Alzheimer's disease
653 2 0 |2 Author
|a molecular farming
653 2 0 |2 Author
|a PMPs
653 2 0 |2 Author
|a value-added biochemicals
653 2 0 |2 Author
|a methodologial strategy
700 1 _ |a Kastenholz, B.
|b 1
|u FZJ
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700 1 _ |a Gilmer, F.
|b 2
|u FZJ
|0 P:(DE-Juel1)VDB461
700 1 _ |a Schurr, U.
|b 3
|u FZJ
|0 P:(DE-Juel1)129402
700 1 _ |a Walter, A.
|b 4
|u FZJ
|0 P:(DE-Juel1)VDB2595
773 _ _ |g Vol. 17, p. 723 - 731
|p 723 - 731
|q 17<723 - 731
|0 PERI:(DE-600)2136373-0
|t Protein and peptide letters
|v 17
|y 2010
|x 0929-8665
856 4 _ |u https://juser.fz-juelich.de/record/6388/files/FZJ-6388.pdf
|z Published final document.
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909 C O |o oai:juser.fz-juelich.de:6388
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913 2 _ |a DE-HGF
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|v Plant Science
|x 0
914 1 _ |y 2010
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
920 1 _ |k ICG-3
|l Phytosphäre
|d 31.10.2010
|g ICG
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980 _ _ |a UNRESTRICTED
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981 _ _ |a I:(DE-Juel1)ICG-3-20090406


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