Journal Article

PreJuSER-6388

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Novel Detection System for Plant Protein Production of Pharmaceuticals and Impact on Conformational Diseases

Nagel, K. A.FZJ* ; Kastenholz, B.FZJ* ; Gilmer, F.FZJ* ; Schurr, U.FZJ* ; Walter, A.FZJ*

2010
Bentham Science Publ. Schiphol

This record in other databases:

Abstract: State-of-the-art biochemistry methods in combination with an automated phenotyping method demonstrate the high potential of transgenic tobacco plants in producing properly-folded therapeutic proteins for the treatment of protein-misfolding diseases (e.g., Alzheimer's disease). This molecular farming approach led to highest protein production of hydroponically-grown tobacco compared to other growth substrates generally used in plant cultivation.

Keyword(s): J ; Protein folding (auto) ; Alzheimer's disease (auto) ; molecular farming (auto) ; PMPs (auto) ; value-added biochemicals (auto) ; methodologial strategy (auto)

Note: Record converted from VDB: 12.11.2012

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Research Program(s):

1. Terrestrische Umwelt (P24)

Appears in the scientific report 2010

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