%0 Journal Article
%A Funke, S. A.
%A Willbold, D.
%T Mirror image phage display - a method to generate D-peptide ligands for use in diagnostic or therapeutical applications?
%J Molecular BioSystems
%V 5
%@ 1742-206X
%C Cambridge
%I Royal Society of Chemistry
%M PreJuSER-6513
%P 783 - 786
%D 2009
%Z This work has been supported by a grant of the Volkswagen-Stiftung to D. W. (I/82 649) and by a grant from the "Prasidentenfond der Helmholtzgemeinschaft'' (HGF, "Virtual Institute of Structural Biology'') to D. W.
%X Mirror image phage display is a straightforward approach to identify new potentially therapeutically active D-enantiomeric peptides. Such D-peptides are more resistant to proteolytic degradation compared to L-peptides. In this review, several examples of mirror image phage display derived D-peptides with therapeutical potential are introduced and discussed.
%K Drug Design
%K Ligands
%K Peptide Library
%K Peptides: chemistry
%K Peptides: therapeutic use
%K Stereoisomerism
%K Ligands (NLM Chemicals)
%K Peptide Library (NLM Chemicals)
%K Peptides (NLM Chemicals)
%K J (WoSType)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:19603110
%U <Go to ISI:>//WOS:000268033800001
%R 10.1039/b904138a
%U https://juser.fz-juelich.de/record/6513