TY  - JOUR
AU  - Funke, S. A.
AU  - Willbold, D.
TI  - Mirror image phage display - a method to generate D-peptide ligands for use in diagnostic or therapeutical applications?
JO  - Molecular BioSystems
VL  - 5
SN  - 1742-206X
CY  - Cambridge
PB  - Royal Society of Chemistry
M1  - PreJuSER-6513
SP  - 783 - 786
PY  - 2009
N1  - This work has been supported by a grant of the Volkswagen-Stiftung to D. W. (I/82 649) and by a grant from the "Prasidentenfond der Helmholtzgemeinschaft'' (HGF, "Virtual Institute of Structural Biology'') to D. W.
AB  - Mirror image phage display is a straightforward approach to identify new potentially therapeutically active D-enantiomeric peptides. Such D-peptides are more resistant to proteolytic degradation compared to L-peptides. In this review, several examples of mirror image phage display derived D-peptides with therapeutical potential are introduced and discussed.
KW  - Drug Design
KW  - Ligands
KW  - Peptide Library
KW  - Peptides: chemistry
KW  - Peptides: therapeutic use
KW  - Stereoisomerism
KW  - Ligands (NLM Chemicals)
KW  - Peptide Library (NLM Chemicals)
KW  - Peptides (NLM Chemicals)
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:19603110
UR  - <Go to ISI:>//WOS:000268033800001
DO  - DOI:10.1039/b904138a
UR  - https://juser.fz-juelich.de/record/6513
ER  -