000807841 001__ 807841 000807841 005__ 20210129222737.0 000807841 0247_ $$2doi$$a10.1093/brain/aww034 000807841 0247_ $$2ISSN$$a0006-8950 000807841 0247_ $$2ISSN$$a1460-2156 000807841 0247_ $$2WOS$$aWOS:000374234900009 000807841 0247_ $$2altmetric$$aaltmetric:6526620 000807841 0247_ $$2pmid$$apmid:27012489 000807841 037__ $$aFZJ-2016-02201 000807841 041__ $$aEnglish 000807841 082__ $$a610 000807841 1001_ $$0P:(DE-Juel1)131720$$aFink, Gereon R.$$b0$$eCorresponding author$$ufzj 000807841 245__ $$aNew hope for ameliorating stroke-induced deficits? 000807841 260__ $$aOxford$$bOxford Univ. Press$$c2016 000807841 3367_ $$2DRIVER$$aarticle 000807841 3367_ $$2DataCite$$aOutput Types/Journal article 000807841 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1472453653_29055 000807841 3367_ $$2BibTeX$$aARTICLE 000807841 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000807841 3367_ $$00$$2EndNote$$aJournal Article 000807841 520__ $$aThis scientific commentary refers to ‘Electrical stimulation of the motor cortex enhances treatment outcome in post-stroke aphasia’ by Meinzer et al. (doi:10.1093/brain/aww002).The overall decline in stroke mortality observed over the past decades is due to both a reduction in stroke incidence, primarily resulting from cardiovascular risk factor interventions, and substantial progress in the acute treatment of stroke (e.g. recanalization due to thrombolysis and thrombectomy, decompressive therapy) as well as patient care (stroke units) (Mozaffarian et al., 2016). These improvements (in particular among people older than 65 years) are mirrored, however, by an increasing number of stroke survivors, who are left with persistent neurological deficits. Despite intensive rehabilitation, at least in countries with well developed healthcare systems, many stroke survivors are left with motor, language, spatial or other neuropsychological sequelae, all of which result in reduced functional independence. Consequently, stroke is the leading cause of acquired long-term disability and globally produces immense health, social and economic burdens (Mozaffarian et al., 2016). While physiotherapy, language therapy and occupational therapy are widely accepted elements of rehabilitation medicine that aim to restore functioning and quality of life in those with physical disabilities or cognitive impairments, novel approaches to rehabilitation are urgently needed. Such therapies may comprise behavioural, pharmacological or technical approaches, the latter including the use of robotic devices as well as non-invasive neuromodulatory techniques [i.e. transcranial magnetic stimulation (TMS) or transcranial direct current stimulation (tDCS)]. In this issue of Brain, Meinzer and colleagues raise new hope for the treatment of post-stroke aphasia by showing that electrical stimulation of the motor cortex [sic!] enhances treatment outcomes (Meinzer et al., 2016). 000807841 536__ $$0G:(DE-HGF)POF3-572$$a572 - (Dys-)function and Plasticity (POF3-572)$$cPOF3-572$$fPOF III$$x0 000807841 588__ $$aDataset connected to CrossRef 000807841 7001_ $$0P:(DE-Juel1)161406$$aGrefkes, Christian$$b1$$ufzj 000807841 7001_ $$0P:(DE-HGF)0$$aWeiss, Peter H.$$b2 000807841 773__ $$0PERI:(DE-600)1474117-9$$a10.1093/brain/aww034$$gVol. 139, no. 4, p. 1002 - 1004$$n4$$p1002 - 1004$$tBrain$$v139$$x1460-2156$$y2016 000807841 8564_ $$uhttps://juser.fz-juelich.de/record/807841/files/1002.full.pdf$$yRestricted 000807841 8564_ $$uhttps://juser.fz-juelich.de/record/807841/files/1002.full.gif?subformat=icon$$xicon$$yRestricted 000807841 8564_ $$uhttps://juser.fz-juelich.de/record/807841/files/1002.full.jpg?subformat=icon-1440$$xicon-1440$$yRestricted 000807841 8564_ $$uhttps://juser.fz-juelich.de/record/807841/files/1002.full.jpg?subformat=icon-180$$xicon-180$$yRestricted 000807841 8564_ $$uhttps://juser.fz-juelich.de/record/807841/files/1002.full.jpg?subformat=icon-640$$xicon-640$$yRestricted 000807841 8564_ $$uhttps://juser.fz-juelich.de/record/807841/files/1002.full.pdf?subformat=pdfa$$xpdfa$$yRestricted 000807841 909CO $$ooai:juser.fz-juelich.de:807841$$pVDB 000807841 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131720$$aForschungszentrum Jülich GmbH$$b0$$kFZJ 000807841 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)161406$$aForschungszentrum Jülich GmbH$$b1$$kFZJ 000807841 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-HGF)0$$aForschungszentrum Jülich GmbH$$b2$$kFZJ 000807841 9131_ $$0G:(DE-HGF)POF3-572$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$v(Dys-)function and Plasticity$$x0 000807841 9141_ $$y2016 000807841 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS 000807841 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences 000807841 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bBRAIN : 2014 000807841 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection 000807841 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index 000807841 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded 000807841 915__ $$0StatID:(DE-HGF)0400$$2StatID$$aAllianz-Lizenz / DFG 000807841 915__ $$0StatID:(DE-HGF)0550$$2StatID$$aNo Authors Fulltext 000807841 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bBRAIN : 2014 000807841 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database 000807841 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews 000807841 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline 000807841 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine 000807841 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz 000807841 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List 000807841 920__ $$lyes 000807841 9201_ $$0I:(DE-Juel1)INM-3-20090406$$kINM-3$$lKognitive Neurowissenschaften$$x0 000807841 980__ $$ajournal 000807841 980__ $$aVDB 000807841 980__ $$aUNRESTRICTED 000807841 980__ $$aI:(DE-Juel1)INM-3-20090406