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@ARTICLE{Vanasschen:811598,
author = {Vanasschen, Christian and Brandt, Marie and Ermert,
Johannes and Coenen, Heinrich Hubert},
title = {{R}adiolabelling with isotopic mixtures of
$^{52g/55}${M}n({II}) as a straight route to stable
manganese complexes for bimodal {PET}/{MR} imaging},
journal = {Dalton transactions},
volume = {45},
number = {4},
issn = {0300-9246},
address = {London},
publisher = {The Royal Society of Chemistry},
reportid = {FZJ-2016-04017},
pages = {1315–1321},
year = {2016},
abstract = {Radiolabelling using isotopic mixtures of 52g/55Mn(ii)
offers fast and easy access to new small molecule PET/MR
tracers, composed of chemically identical reporting units.
trans-1,2-Diaminocyclohexane-N,N,N[prime or minute],N[prime
or minute]-tetraacetic acid (CDTA) was radiolabelled with
carrier-added 52gMn(ii) in $>99\%$ radiochemical yield,
producing the first manganese-based bimodal PET/MR probe.
The Mn-CDTA chelate was shown to be very stable to air
oxidation and sufficiently inert to decomplexation in blood
serum. These data sparked our interest in functionalized
CDTA ligands for the design of optimized PET/MR tracers.},
cin = {INM-5},
ddc = {540},
cid = {I:(DE-Juel1)INM-5-20090406},
pnm = {573 - Neuroimaging (POF3-573)},
pid = {G:(DE-HGF)POF3-573},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000369088000004},
pubmed = {pmid:26685974},
doi = {10.1039/C5DT04270D},
url = {https://juser.fz-juelich.de/record/811598},
}