Journal Article FZJ-2016-05392

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Lissodendrins A and B: 2-Amino­imidazole Alkaloids from the Marine Sponge Lissodendoryx (Acanthodoryx) fibrosa

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2016
Wiley-VCH Verl. Weinheim

European journal of organic chemistry 2016(4), 639 - 643 () [10.1002/ejoc.201501250]

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Abstract: Chemical investigation of the Indonesian sponge Lissodendoryx (Acanthodoryx) fibrosa yielded the new 2-aminoimidazole alkaloids lissodendrins A (1) and B (2). Their structures were unambiguously determined by extensive NMR spectroscopic (1H, 13C, ROESY and long-range HMBC) studies and mass spectrometric (HRESIMS/MS) data. Lissodendrins A (1) and B (2) possess unprecedented skeletons with the latter compound bearing a (p-hydroxyphenyl)glyoxal moiety, which is rarely encountered in natural products. A plausible biosynthetic pathway for these new metabolites is proposed.

Classification:

Contributing Institute(s):
  1. Strukturbiochemie (ICS-6)
Research Program(s):
  1. 552 - Engineering Cell Function (POF3-552) (POF3-552)

Appears in the scientific report 2016
Database coverage:
Medline ; Current Contents - Physical, Chemical and Earth Sciences ; IF < 5 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection
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 Record created 2016-10-14, last modified 2021-01-29


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