%0 Journal Article
%A Schmidt, Sandy
%A Pedroso de Almeida, Tiago
%A Rother, Dörte
%A Hollmann, Frank
%T Towards environmentally acceptable synthesis of chiral α-hydroxy ketones via oxidase-lyase cascades
%J Green chemistry
%V 19
%N 5
%@ 1463-9270
%C Cambridge
%I RSC
%M FZJ-2017-01589
%P 1226–1229
%D 2017
%X The one-pot multistep enzymatic oxidation of aliphatic andbenzylic alcohols to the corresponding aldehydes combined withtheir subsequent carboligation to chiral α-hydroxy ketones hasbeen exemplarily evaluated in terms of being a “green” biocatalyticapproach. Besides the potential to start from bio-derived alcohols,this concept avoids the direct use of the reactive aldehyde intermediates,enables addition of high substrate concentrations in oneliquid phase while maintaining enzyme activity and enables a simplifiedproduct isolation with diminished waste formation
%F PUB:(DE-HGF)16
%9 Journal Article
%U <Go to ISI:>//WOS:000396144200003
%R 10.1039/C7GC00020K
%U https://juser.fz-juelich.de/record/827464