Journal Article

FZJ-2017-01589

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Towards environmentally acceptable synthesis of chiral α-hydroxy ketones via oxidase-lyase cascades

Schmidt, S. ; Pedroso de Almeida, T. ; Rother, D.FZJ* ; Hollmann, F. (Corresponding author)

2017
RSC Cambridge

This record in other databases:    

Please use a persistent id in citations: doi:10.1039/C7GC00020K

Abstract: The one-pot multistep enzymatic oxidation of aliphatic andbenzylic alcohols to the corresponding aldehydes combined withtheir subsequent carboligation to chiral α-hydroxy ketones hasbeen exemplarily evaluated in terms of being a “green” biocatalyticapproach. Besides the potential to start from bio-derived alcohols,this concept avoids the direct use of the reactive aldehyde intermediates,enables addition of high substrate concentrations in oneliquid phase while maintaining enzyme activity and enables a simplifiedproduct isolation with diminished waste formation

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Contributing Institute(s):

1. Biotechnologie (IBG-1)

Research Program(s):

1. 581 - Biotechnology (POF3-581) (POF3-581)

Appears in the scientific report 2017

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Database coverage:
; Allianz-Lizenz / DFG ; Current Contents - Physical, Chemical and Earth Sciences ; Ebsco Academic Search ; IF >= 5 ; JCR ; NCBI Molecular Biology Database ; Nationallizenz ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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