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@ARTICLE{Schmidt:827464,
author = {Schmidt, Sandy and Pedroso de Almeida, Tiago and Rother,
Dörte and Hollmann, Frank},
title = {{T}owards environmentally acceptable synthesis of chiral
α-hydroxy ketones via oxidase-lyase cascades},
journal = {Green chemistry},
volume = {19},
number = {5},
issn = {1463-9270},
address = {Cambridge},
publisher = {RSC},
reportid = {FZJ-2017-01589},
pages = {1226–1229},
year = {2017},
abstract = {The one-pot multistep enzymatic oxidation of aliphatic
andbenzylic alcohols to the corresponding aldehydes combined
withtheir subsequent carboligation to chiral α-hydroxy
ketones hasbeen exemplarily evaluated in terms of being a
“green” biocatalyticapproach. Besides the potential to
start from bio-derived alcohols,this concept avoids the
direct use of the reactive aldehyde intermediates,enables
addition of high substrate concentrations in oneliquid phase
while maintaining enzyme activity and enables a
simplifiedproduct isolation with diminished waste formation},
cin = {IBG-1},
ddc = {540},
cid = {I:(DE-Juel1)IBG-1-20101118},
pnm = {581 - Biotechnology (POF3-581)},
pid = {G:(DE-HGF)POF3-581},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000396144200003},
doi = {10.1039/C7GC00020K},
url = {https://juser.fz-juelich.de/record/827464},
}