| Home > Publications database > Towards environmentally acceptable synthesis of chiral α-hydroxy ketones via oxidase-lyase cascades > print |
| 001 | 827464 | ||
| 005 | 20210129225836.0 | ||
| 024 | 7 | _ | |a 10.1039/C7GC00020K |2 doi |
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| 024 | 7 | _ | |a 1463-9270 |2 ISSN |
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| 100 | 1 | _ | |a Schmidt, Sandy |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a Towards environmentally acceptable synthesis of chiral α-hydroxy ketones via oxidase-lyase cascades |
| 260 | _ | _ | |a Cambridge |c 2017 |b RSC |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 520 | _ | _ | |a The one-pot multistep enzymatic oxidation of aliphatic andbenzylic alcohols to the corresponding aldehydes combined withtheir subsequent carboligation to chiral α-hydroxy ketones hasbeen exemplarily evaluated in terms of being a “green” biocatalyticapproach. Besides the potential to start from bio-derived alcohols,this concept avoids the direct use of the reactive aldehyde intermediates,enables addition of high substrate concentrations in oneliquid phase while maintaining enzyme activity and enables a simplifiedproduct isolation with diminished waste formation |
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| 700 | 1 | _ | |a Hollmann, Frank |0 P:(DE-HGF)0 |b 3 |e Corresponding author |
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