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245 _ _ |a Towards environmentally acceptable synthesis of chiral α-hydroxy ketones via oxidase-lyase cascades
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520 _ _ |a The one-pot multistep enzymatic oxidation of aliphatic andbenzylic alcohols to the corresponding aldehydes combined withtheir subsequent carboligation to chiral α-hydroxy ketones hasbeen exemplarily evaluated in terms of being a “green” biocatalyticapproach. Besides the potential to start from bio-derived alcohols,this concept avoids the direct use of the reactive aldehyde intermediates,enables addition of high substrate concentrations in oneliquid phase while maintaining enzyme activity and enables a simplifiedproduct isolation with diminished waste formation
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700 1 _ |a Hollmann, Frank
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