TY - JOUR AU - Rose, Michael AU - Kloten, Vera AU - Noetzel, Erik AU - Gola, Lukas AU - Ehling, Josef AU - Heide, Timon AU - Meurer, Steffen K. AU - Gaiko-Shcherbak, Aljona AU - Sechi, Antonio S. AU - Huth, Sebastian AU - Weiskirchen, Ralf AU - Klaas, Oliver AU - Antonopoulos, Wiebke AU - Lin, Qiong AU - Wagner, Wolfgang AU - Veeck, Jürgen AU - Gremse, Felix AU - Steitz, Julia AU - Knüchel, Ruth AU - Dahl, Edgar TI - ITIH5 mediates epigenetic reprogramming of breast cancer cells JO - Molecular cancer VL - 16 IS - 1 SN - 1476-4598 CY - London PB - Biomed Central M1 - FZJ-2017-02215 SP - 44 PY - 2017 AB - Extracellular matrix (ECM) is known to maintain epithelial integrity. In carcinogenesis ECM degradation triggers metastasis by controlling migration and differentiation including cancer stem cell (CSC) characteristics. The ECM-modulator inter- α-trypsin inhibitor heavy chain family member five (ITIH5) was recently identified as tumor suppressor potentially involved in impairing breast cancer progression but molecular mechanisms underlying its function are still elusive. LB - PUB:(DE-HGF)16 UR - <Go to ISI:>//WOS:000397799800002 C6 - pmid:28231808 DO - DOI:10.1186/s12943-017-0610-2 UR - https://juser.fz-juelich.de/record/828247 ER -