TY  - JOUR
AU  - Gorshkova, Yu. E.
AU  - Kuklin, A. I.
AU  - Gordeliy, Valentin
TI  - Structure and phase transitions of DMPC multilamellar vesicles in the presence of Ca2+ ions
JO  - Journal of surface investigation
VL  - 11
IS  - 1
SN  - 1027-4510
CY  - Moscow
PB  - MAIK Nauka/Interperiodics Publ.
M1  - FZJ-2017-04110
SP  - 27–37
PY  - 2017
AB  - Results obtained via small-angle neutron scattering studies of the influence of calcium ions on the structure and phase transitions of phospholipid membranes are presented. The main phase transition temperature of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (1 wt %) multilamellar vesicles is demonstrated to increase by more than 1°C even when the calcium-ion content of the solution is low (0.1 mM). Detailed analysis of the multilamellar vesicles transition between “bound” and “unbound” state indicates the continuous character of the investigated process in both liquid and gel phases. The critical Ca2+ ion concentrations which initiate the destruction of the multilamellar structures and the formation of unilamellar vesicles are found to be ~0.3 mM in the gel and ~0.4–0.5 mM in the liquid-crystal phases during heating and ~0.5 mM in the phases under study upon cooling.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000396389600003
DO  - DOI:10.1134/S1027451016050499
UR  - https://juser.fz-juelich.de/record/834109
ER  -