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000836330 0247_ $$2doi$$a10.1007/978-3-319-42202-2_30
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000836330 041__ $$aEnglish
000836330 1001_ $$0P:(DE-HGF)0$$aKiessling, Fabian$$b0$$eEditor
000836330 245__ $$aImaging in Neurology Research III: Neurodegenerative Diseases
000836330 260__ $$aCham$$bSpringer International Publishing$$c2017
000836330 29510 $$aSmall Animal Imaging / Kiessling, Fabian (Editor) ; Cham : Springer International Publishing, 2017, Chapter 30 ; ISBN: 978-3-319-42200-8 ; doi:10.1007/978-3-319-42202-2
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000836330 3367_ $$0PUB:(DE-HGF)7$$2PUB:(DE-HGF)$$aContribution to a book$$bcontb$$mcontb$$s1501585101_13623
000836330 500__ $$aLiteraturangaben; English, Second Edition
000836330 520__ $$aPositron emission tomography (PET) plays an outstanding role among imaging technologies since it enables visualization of physiological and pathophysiological processes at the molecular level in real time. Moreover, it combines low invasiveness with high sensitivity, and numerous biological processes can be measured repeatedly and quantitatively. Therefore, it is ideally suited for translational animal research to investigate different pathologies. Especially neurodegenerative diseases are of particular interest since a plethora of imaging agents exist (Table 30.1), which allow to investigate different molecular targets involved in neurodegenerative processes. Furthermore, various animal models with neurodegenerative diseases are available, facilitating to elucidate dysfunctions associated with the progression of neurodegeneration. Above all, small animal models of Alzheimer’s and Parkinson’s disease are mainly used in this field since they are the most common pathologies of neurodegenerative diseases
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000836330 7001_ $$0P:(DE-HGF)0$$aPichler, Bernd J.$$b1$$eEditor
000836330 7001_ $$0P:(DE-HGF)0$$aHauff, Peter$$b2$$eEditor
000836330 7001_ $$0P:(DE-HGF)0$$aEndepols, Heike$$b3
000836330 7001_ $$0P:(DE-Juel1)166419$$aNeumaier, Bernd$$b4$$ufzj
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