Contribution to a book

FZJ-2017-05451

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Imaging in Neurology Research III: Neurodegenerative Diseases

Kiessling, F. (Editor) ; Pichler, B. J. (Editor) ; Hauff, P. (Editor) ; Endepols, H. ; Neumaier, B.FZJ*

2017
Springer International Publishing Cham
ISBN: 978-3-319-42202-2, 9783319422022 (electronic)

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Please use a persistent id in citations: doi:10.1007/978-3-319-42202-2_30

Abstract: Positron emission tomography (PET) plays an outstanding role among imaging technologies since it enables visualization of physiological and pathophysiological processes at the molecular level in real time. Moreover, it combines low invasiveness with high sensitivity, and numerous biological processes can be measured repeatedly and quantitatively. Therefore, it is ideally suited for translational animal research to investigate different pathologies. Especially neurodegenerative diseases are of particular interest since a plethora of imaging agents exist (Table 30.1), which allow to investigate different molecular targets involved in neurodegenerative processes. Furthermore, various animal models with neurodegenerative diseases are available, facilitating to elucidate dysfunctions associated with the progression of neurodegeneration. Above all, small animal models of Alzheimer’s and Parkinson’s disease are mainly used in this field since they are the most common pathologies of neurodegenerative diseases

Keyword(s): Bildgebendes Verfahren ; Tiermodell

Note: Literaturangaben; English, Second Edition

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Contributing Institute(s):

1. Nuklearchemie (INM-5)

Research Program(s):

1. 573 - Neuroimaging (POF3-573) (POF3-573)

Appears in the scientific report 2017

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