TY  - CHAP
AU  - Endepols, Heike
AU  - Neumaier, Bernd
A3  - Kiessling, Fabian
A3  - Pichler, Bernd J.
A3  - Hauff, Peter
TI  - Imaging in Neurology Research III: Neurodegenerative Diseases
CY  - Cham
PB  - Springer International Publishing
M1  - FZJ-2017-05451
SN  - 978-3-319-42202-2
SP  - 761-772
PY  - 2017
N1  - Literaturangaben; English, Second Edition
AB  - Positron emission tomography (PET) plays an outstanding role among imaging technologies since it enables visualization of physiological and pathophysiological processes at the molecular level in real time. Moreover, it combines low invasiveness with high sensitivity, and numerous biological processes can be measured repeatedly and quantitatively. Therefore, it is ideally suited for translational animal research to investigate different pathologies. Especially neurodegenerative diseases are of particular interest since a plethora of imaging agents exist (Table 30.1), which allow to investigate different molecular targets involved in neurodegenerative processes. Furthermore, various animal models with neurodegenerative diseases are available, facilitating to elucidate dysfunctions associated with the progression of neurodegeneration. Above all, small animal models of Alzheimer’s and Parkinson’s disease are mainly used in this field since they are the most common pathologies of neurodegenerative diseases
KW  - Bildgebendes Verfahren (gnd)
KW  - Tiermodell (gnd)
LB  - PUB:(DE-HGF)7
DO  - DOI:10.1007/978-3-319-42202-2_30
UR  - https://juser.fz-juelich.de/record/836330
ER  -