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@INBOOK{Kiessling:836330,
author = {Endepols, Heike and Neumaier, Bernd},
editor = {Kiessling, Fabian and Pichler, Bernd J. and Hauff, Peter},
title = {{I}maging in {N}eurology {R}esearch {III}:
{N}eurodegenerative {D}iseases},
address = {Cham},
publisher = {Springer International Publishing},
reportid = {FZJ-2017-05451},
isbn = {978-3-319-42202-2},
pages = {761-772},
year = {2017},
note = {Literaturangaben; English, Second Edition},
comment = {Small Animal Imaging / Kiessling, Fabian (Editor) ; Cham :
Springer International Publishing, 2017, Chapter 30 ; ISBN:
978-3-319-42200-8 ; doi:10.1007/978-3-319-42202-2},
booktitle = {Small Animal Imaging / Kiessling,
Fabian (Editor) ; Cham : Springer
International Publishing, 2017, Chapter
30 ; ISBN: 978-3-319-42200-8 ;
doi:10.1007/978-3-319-42202-2},
abstract = {Positron emission tomography (PET) plays an outstanding
role among imaging technologies since it enables
visualization of physiological and pathophysiological
processes at the molecular level in real time. Moreover, it
combines low invasiveness with high sensitivity, and
numerous biological processes can be measured repeatedly and
quantitatively. Therefore, it is ideally suited for
translational animal research to investigate different
pathologies. Especially neurodegenerative diseases are of
particular interest since a plethora of imaging agents exist
(Table 30.1), which allow to investigate different molecular
targets involved in neurodegenerative processes.
Furthermore, various animal models with neurodegenerative
diseases are available, facilitating to elucidate
dysfunctions associated with the progression of
neurodegeneration. Above all, small animal models of
Alzheimer’s and Parkinson’s disease are mainly used in
this field since they are the most common pathologies of
neurodegenerative diseases},
keywords = {Bildgebendes Verfahren (gnd) / Tiermodell (gnd)},
cin = {INM-5},
cid = {I:(DE-Juel1)INM-5-20090406},
pnm = {573 - Neuroimaging (POF3-573)},
pid = {G:(DE-HGF)POF3-573},
typ = {PUB:(DE-HGF)7},
doi = {10.1007/978-3-319-42202-2_30},
url = {https://juser.fz-juelich.de/record/836330},
}