Journal Article

FZJ-2017-08333

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Psychiatric Genomics: An Update and an Agenda

Sullivan, P. F. (Corresponding author) ; Agrawal, A. ; Bulik, C. M. ; Andreassen, O. A. ; Børglum, A. D. ; Breen, G. ; Cichon, S.FZJ* ; Edenberg, H. J. ; Faraone, S. V. ; Gelernter, J. ; Mathews, C. A. ; Nievergelt, C. M. ; Smoller, J. W. ; O'Donovan, M. C. ; Consortium, P. G. (Collaboration Author)

2017
HighWire Press Stanford, Calif.

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Please use a persistent id in citations: doi:10.1176/appi.ajp.2017.17030283

Abstract: The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of psychiatry. This global effort is dedicated to rapid progress and open science, and in the past decade it has delivered an increasing flow of new knowledge about the fundamental basis of common psychiatric disorders. The PGC has recently commenced a program of research designed to deliver 'actionable' findings-genomic results that 1) reveal fundamental biology, 2) inform clinical practice, and 3) deliver new therapeutic targets. The central idea of the PGC is to convert the family history risk factor into biologically, clinically, and therapeutically meaningful insights. The emerging findings suggest that we are entering a phase of accelerated genetic discovery for multiple psychiatric disorders. These findings are likely to elucidate the genetic portions of these truly complex traits, and this knowledge can then be mined for its relevance for improved therapeutics and its impact on psychiatric practice within a precision medicine framework.

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Contributing Institute(s):

1. Strukturelle und funktionelle Organisation des Gehirns (INM-1)

Research Program(s):

1. 571 - Connectivity and Activity (POF3-571) (POF3-571)

Appears in the scientific report 2017

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Database coverage:
; BIOSIS Previews ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; Current Contents - Social and Behavioral Sciences ; Ebsco Academic Search ; IF >= 10 ; JCR ; NCBI Molecular Biology Database ; Nationallizenz ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Social Sciences Citation Index ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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