Gast ::
| Hauptseite > Publikationsdatenbank > New amide and dioxopiperazine derivatives from leaves of Breynia nivosa > print |
| Hauptseite > Publikationsdatenbank > New amide and dioxopiperazine derivatives from leaves of Breynia nivosa > print |
| 001 | 841557 | ||
| 005 | 20210129232033.0 | ||
| 024 | 7 | _ | |a 10.1016/j.fitote.2017.08.009 |2 doi |
| 024 | 7 | _ | |a pmid:28830789 |2 pmid |
| 024 | 7 | _ | |a WOS:000413383500004 |2 WOS |
| 024 | 7 | _ | |a altmetric:24256673 |2 altmetric |
| 037 | _ | _ | |a FZJ-2017-08595 |
| 082 | _ | _ | |a 570 |
| 100 | 1 | _ | |a Umeokoli, Blessing O. |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a New amide and dioxopiperazine derivatives from leaves of Breynia nivosa |
| 260 | _ | _ | |a Amsterdam [u.a.] |c 2017 |b Elsevier Science |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1520841777_25963 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a The first chemical investigation of leaves of Breynia nivosa from Nigeria resulted in the isolation of two new amide derivatives breynivosamides A and B (1 and 2) and two new dioxopiperazine derivatives breynivosines A and B (4 and 5) together with seven known compounds (3, 6–11). The structures of the new compounds were elucidated by 1D, 2D NMR and HRESIMS data as well as by comparison with the literature. All isolated compounds were tested for the cytotoxic and antimicrobial activities. Only cristatin A (6) showed cytotoxicity against the L5178Y mouse lymphoma cell line with an IC50 value of 13.9 μM while breynivosamide A (1) exhibited moderate antimicrobial activity against Mycobacterium tuberculosis with an MIC value of 25 μM. |
| 536 | _ | _ | |a 551 - Functional Macromolecules and Complexes (POF3-551) |0 G:(DE-HGF)POF3-551 |c POF3-551 |f POF III |x 0 |
| 700 | 1 | _ | |a Onyegbule, Felix A. |0 P:(DE-HGF)0 |b 1 |
| 700 | 1 | _ | |a Okoye, Festus B. C. |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Wang, Hao |0 P:(DE-HGF)0 |b 3 |
| 700 | 1 | _ | |a Kalscheuer, Rainer |0 P:(DE-HGF)0 |b 4 |
| 700 | 1 | _ | |a Müller, Werner E. G. |0 P:(DE-HGF)0 |b 5 |
| 700 | 1 | _ | |a Hartmann, Rudolf |0 P:(DE-Juel1)132001 |b 6 |u fzj |
| 700 | 1 | _ | |a Liu, Zhen |0 P:(DE-HGF)0 |b 7 |e Corresponding author |
| 700 | 1 | _ | |a Proksch, Peter |0 P:(DE-HGF)0 |b 8 |e Corresponding author |
| 773 | _ | _ | |a 10.1016/j.fitote.2017.08.009 |0 PERI:(DE-600)2027649-7 |p 16-19 |t Fitoterapia |v 122 |y 2017 |x 0367-326X |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/841557/files/1-s2.0-S0367326X17306135-main.pdf |y Restricted |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/841557/files/1-s2.0-S0367326X17306135-main.gif?subformat=icon |x icon |y Restricted |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/841557/files/1-s2.0-S0367326X17306135-main.jpg?subformat=icon-1440 |x icon-1440 |y Restricted |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/841557/files/1-s2.0-S0367326X17306135-main.jpg?subformat=icon-180 |x icon-180 |y Restricted |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/841557/files/1-s2.0-S0367326X17306135-main.jpg?subformat=icon-640 |x icon-640 |y Restricted |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/841557/files/1-s2.0-S0367326X17306135-main.pdf?subformat=pdfa |x pdfa |y Restricted |
| 909 | C | O | |o oai:juser.fz-juelich.de:841557 |p VDB |
| 910 | 1 | _ | |a Forschungszentrum Jülich |0 I:(DE-588b)5008462-8 |k FZJ |b 6 |6 P:(DE-Juel1)132001 |
| 913 | 1 | _ | |a DE-HGF |b Key Technologies |l BioSoft – Fundamentals for future Technologies in the fields of Soft Matter and Life Sciences |1 G:(DE-HGF)POF3-550 |0 G:(DE-HGF)POF3-551 |2 G:(DE-HGF)POF3-500 |v Functional Macromolecules and Complexes |x 0 |4 G:(DE-HGF)POF |3 G:(DE-HGF)POF3 |
| 914 | 1 | _ | |y 2018 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0310 |2 StatID |b NCBI Molecular Biology Database |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0600 |2 StatID |b Ebsco Academic Search |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b ASC |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Thomson Reuters Master Journal List |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |
| 915 | _ | _ | |a IF < 5 |0 StatID:(DE-HGF)9900 |2 StatID |
| 920 | 1 | _ | |0 I:(DE-Juel1)ICS-6-20110106 |k ICS-6 |l Strukturbiochemie |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-Juel1)ICS-6-20110106 |
| 980 | _ | _ | |a UNRESTRICTED |
| 981 | _ | _ | |a I:(DE-Juel1)IBI-7-20200312 |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|