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@ARTICLE{Knigs:843844,
author = {Königs, Uwe and Humpert, Swen and Spahn, Ingo and Qaim,
Syed M. and Neumaier, Bernd},
title = {{I}solation of high purity 73{S}e using solid phase
extraction after selective 4,5-[73{S}e]benzopiazselenol
formation with aminonaphthalene},
journal = {Radiochimica acta},
volume = {106},
number = {6},
issn = {0033-8230},
address = {Berlin},
publisher = {De Gruyter},
reportid = {FZJ-2018-01383},
pages = {497–505},
year = {2018},
abstract = {A fast and efficient process for the productionof the PET
radionuclide 73Se was developed using 75Se as asurrogate.
75Se was separated from proton irradiated arsenictrioxide by
reaction with 2,3-diaminonaphthalene
to4,5-[75Se]benzopiazelenol. This compound was purifiedusing
SPE column chromatography and subsequentlydecomposed with
hydrogen peroxide. For further chemicalconversions
[75Se]selenite was reduced to elemental[75Se]selenium by
either using thiosulfate or sulfur dioxide.The recovery
yield of 75Se from the target amountedto 43 $\%.$ The
utility of the isolated 75Se for radiosyntheseswas
demonstrated by the successful preparation of
[75Se]selenomethionine.The methodology developed using
75Sewas successfully transformed to 73Se.},
cin = {INM-5},
ddc = {540},
cid = {I:(DE-Juel1)INM-5-20090406},
pnm = {573 - Neuroimaging (POF3-573)},
pid = {G:(DE-HGF)POF3-573},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000433962300005},
doi = {10.1515/ract-2017-2864},
url = {https://juser.fz-juelich.de/record/843844},
}