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@ARTICLE{Yang:844160,
      author       = {Yang, Ge and Yu, Kun and Kubicek, Jan and Labahn, Jörg},
      title        = {{D}ata on solubilization, identification, and thermal
                      stability of human {P}resenilin-2},
      journal      = {Data in Brief},
      volume       = {17},
      issn         = {2352-3409},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {FZJ-2018-01626},
      pages        = {626 - 630},
      year         = {2018},
      abstract     = {The data presented here are related to the research article
                      entitled “Expression, purification, and preliminary
                      characterization of human presenilin-2" [1].Human
                      Presenilin-2 is the catalytic subunit of γ-secretase and a
                      possible calcium leakage channel (Kimberly et al., 2000; Tu
                      et al., 2006) [2,3]. HisPS2 which was obtained by
                      overexpression in E. coli strain C43 (DE3) was extracted by
                      detergent solubilisation. The sample isolation efficiency by
                      detergents and the protein identification by mass
                      spectrometry and western blot are described.This data
                      article describes the near and far UV circular dichroism
                      measurements and the data deconvolution in terms of
                      secondary structure at 4 and 98 °C. Also, a refolding
                      spectrum is presented.The raw CD spectra used for
                      deconvolution of the helix and stand segments and average
                      length are deposited into Protein Circular Dichroism Data
                      Bank with PCDDBid: CD0005962000 (4 °C far UV),
                      CD0005963000 (98 °C far UV), CD0005964000 (back to
                      4 °C far UV) and CD0005965000 (4 °C near UV CD).},
      cin          = {ICS-6},
      ddc          = {570},
      cid          = {I:(DE-Juel1)ICS-6-20110106},
      pnm          = {551 - Functional Macromolecules and Complexes (POF3-551)},
      pid          = {G:(DE-HGF)POF3-551},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29552611},
      UT           = {WOS:000449763000081},
      doi          = {10.1016/j.dib.2018.01.039},
      url          = {https://juser.fz-juelich.de/record/844160},
}