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@ARTICLE{Adly:844806,
      author       = {Adly, Nouran and Weidlich, Sabrina and Seyock, Silke and
                      Brings, Fabian and Yakushenko, Alexey and Offenhäusser,
                      Andreas and Wolfrum, Bernhard},
      title        = {{P}rinted microelectrode arrays on soft materials: from
                      {PDMS} to hydrogels},
      journal      = {npj flexible electronics},
      volume       = {2},
      number       = {1},
      issn         = {2397-4621},
      address      = {London},
      publisher    = {Springer Nature},
      reportid     = {FZJ-2018-02180},
      pages        = {15},
      year         = {2018},
      abstract     = {Microelectrode arrays (MEAs) provide promising
                      opportunities to study electrical signals in neuronal and
                      cardiac cell networks, restore sensory function, or treat
                      disorders of the nervous system. Nevertheless, most of the
                      currently investigated devices rely on silicon or polymer
                      materials, which neither physically mimic nor mechanically
                      match the structure of living tissue, causing inflammatory
                      response or loss of functionality. Here, we present a new
                      method for developing soft MEAs as bioelectronic interfaces.
                      The functional structures are directly deposited on PDMS-,
                      agarose-, and gelatin-based substrates using ink-jet
                      printing as a patterning tool. We demonstrate the
                      versatility of this approach by printing high-resolution
                      carbon MEAs on PDMS and hydrogels. The soft MEAs are used
                      for in vitro extracellular recording of action potentials
                      from cardiomyocyte-like HL-1 cells. Our results represent an
                      important step toward the design of next-generation
                      bioelectronic interfaces in a rapid prototyping approach.},
      cin          = {ICS-8},
      ddc          = {621.3},
      cid          = {I:(DE-Juel1)ICS-8-20110106},
      pnm          = {552 - Engineering Cell Function (POF3-552)},
      pid          = {G:(DE-HGF)POF3-552},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000619050900015},
      doi          = {10.1038/s41528-018-0027-z},
      url          = {https://juser.fz-juelich.de/record/844806},
}