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@ARTICLE{Rabehi:848161,
author = {Rabehi, Amine and Garlan, Benjamin and Achtsnicht, Stefan
and Krause, Hans-Joachim and Offenhäusser, Andreas and Ngo,
Kieu and Neveu, Sophie and Graff-Dubois, Stephanie and
Kokabi, Hamid},
title = {{M}agnetic {D}etection {S}tructure for {L}ab-on-{C}hip
{A}pplications {B}ased on the {F}requency {M}ixing
{T}echnique},
journal = {Sensors},
volume = {18},
number = {6},
issn = {1424-8220},
address = {Basel},
publisher = {MDPI},
reportid = {FZJ-2018-03427},
pages = {1747 -},
year = {2018},
abstract = {A magnetic frequency mixing technique with a set of
miniaturized planar coils was investigated for use with a
completely integrated Lab-on-Chip (LoC) pathogen sensing
system. The system allows the detection and quantification
of superparamagnetic beads. Additionally, in terms of
magnetic nanoparticle characterization ability, the system
can be used for immunoassays using the beads as markers.
Analytical calculations and simulations for both excitation
and pick-up coils are presented; the goal was to investigate
the miniaturization of simple and cost-effective planar
spiral coils. Following these calculations, a Printed
Circuit Board (PCB) prototype was designed, manufactured,
and tested for limit of detection, linear response, and
validation of theoretical concepts. Using the magnetic
frequency mixing technique, a limit of detection of 15
µg/mL of 20 nm core-sized nanoparticles was achieved
without any shielding.},
cin = {ICS-8},
ddc = {620},
cid = {I:(DE-Juel1)ICS-8-20110106},
pnm = {523 - Controlling Configuration-Based Phenomena (POF3-523)},
pid = {G:(DE-HGF)POF3-523},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29844260},
UT = {WOS:000436774300081},
doi = {10.3390/s18061747},
url = {https://juser.fz-juelich.de/record/848161},
}