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@ARTICLE{Sadoine:849675,
author = {Sadoine, Mayuri and Cerminara, Michele and Fitter, Jörg
and Katranidis, Alexandros},
title = {{P}reparation of {C}ell-free {S}ynthesized {P}roteins
{S}electively {D}ouble {L}abeled for {S}ingle-molecule
{FRET} {S}tudies},
journal = {Bio-protocol},
volume = {8},
number = {12},
issn = {2331-8325},
address = {Sunnyvale, CA},
publisher = {bio-protocol.org},
reportid = {FZJ-2018-03811},
pages = {1},
year = {2018},
abstract = {Single-molecule FRET (smFRET) is a powerful tool to
investigate molecular structures and conformational changes
of biological molecules. The technique requires protein
samples that are site-specifically equipped with a pair of
donor and acceptor fluorophores. Here, we present a detailed
protocol for preparing double-labeled proteins for smFRET
studies. The protocol describes two cell-free approaches to
achieve a selective label scheme that allows the highest
possible accuracy in inter‐dye distance determination.},
cin = {ICS-5},
ddc = {570},
cid = {I:(DE-Juel1)ICS-5-20110106},
pnm = {551 - Functional Macromolecules and Complexes (POF3-551)},
pid = {G:(DE-HGF)POF3-551},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000457962400003},
doi = {10.21769/BioProtoc.2881},
url = {https://juser.fz-juelich.de/record/849675},
}