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@ARTICLE{Rosen:850148,
author = {Rosen, Jurij and Blau, Tobias and Grau, Stefan J. and
Barbe, Michael T. and Fink, Gereon Rudolf and Galldiks,
Norbert},
title = {{E}xtracranial {M}etastases of a {C}erebral {G}lioblastoma:
{A} {C}ase {R}eport and {R}eview of the {L}iterature},
journal = {Case reports in oncology},
volume = {11},
number = {2},
issn = {1662-6575},
address = {Basel},
publisher = {Karger},
reportid = {FZJ-2018-04226},
pages = {591 - 600},
year = {2018},
abstract = {The glioblastoma, a malignant human brain tumor, is known
for its devastating intracranial progress and its dismal
prognosis. Whereas treatment and research are most
prominently focused on the primary tumor lesion, in recent
years evidence has accumulated that points to the rare
occurrence of extracranial glioblastoma metastases. We here
present a case of a female patient with a known glioblastoma
who was detected to harbor multiple metastases in the bones,
lung, pleura, liver, mesentery, and the subcutaneous soft
tissue. Pathogenetically, these metastatic lesions developed
most probably after a local progression of the left temporal
glioblastoma through the skull base, thus getting access to
the systemic lymphatics. Similar cases of extensive
glioblastoma metastization, their putative underlying
mechanisms, and implications for clinical care are
discussed.},
cin = {INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30283316},
UT = {WOS:000455063400052},
doi = {10.1159/000492111},
url = {https://juser.fz-juelich.de/record/850148},
}