Journal Article

FZJ-2018-04226

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Extracranial Metastases of a Cerebral Glioblastoma: A Case Report and Review of the Literature

Rosen, J. ; Blau, T. ; Grau, S. ; Barbe, M. ; Fink, G. R.FZJ* ; Galldiks, N. (Corresponding author)FZJ*

2018
Karger Basel

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Please use a persistent id in citations: http://hdl.handle.net/2128/19691  doi:10.1159/000492111

Abstract: The glioblastoma, a malignant human brain tumor, is known for its devastating intracranial progress and its dismal prognosis. Whereas treatment and research are most prominently focused on the primary tumor lesion, in recent years evidence has accumulated that points to the rare occurrence of extracranial glioblastoma metastases. We here present a case of a female patient with a known glioblastoma who was detected to harbor multiple metastases in the bones, lung, pleura, liver, mesentery, and the subcutaneous soft tissue. Pathogenetically, these metastatic lesions developed most probably after a local progression of the left temporal glioblastoma through the skull base, thus getting access to the systemic lymphatics. Similar cases of extensive glioblastoma metastization, their putative underlying mechanisms, and implications for clinical care are discussed.

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Contributing Institute(s):

1. Kognitive Neurowissenschaften (INM-3)

Research Program(s):

1. 572 - (Dys-)function and Plasticity (POF3-572) (POF3-572)

Appears in the scientific report 2018

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Database coverage:
; ; ; ; DOAJ Seal ; Emerging Sources Citation Index ; SCOPUS ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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