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@ARTICLE{Hoore:850924,
author = {Hoore, Masoud and Yaya, François and Podgorski, Thomas and
Wagner, Christian and Gompper, Gerhard and Fedosov, Dmitry
A.},
title = {{E}ffect of spectrin network elasticity on the shapes of
erythrocyte doublets},
journal = {Soft matter},
volume = {14},
number = {30},
issn = {1744-6848},
address = {London},
publisher = {Royal Soc. of Chemistry},
reportid = {FZJ-2018-04655},
pages = {6278 - 6289},
year = {2018},
abstract = {Red blood cell (RBC) aggregates play an important role in
determining blood rheology. RBCs in plasma or polymer
solution interact attractively to form various shapes of RBC
doublets, where the attractive interactions can be varied by
changing the solution conditions. A systematic numerical
study on RBC doublet formation is performed, which takes
into account the shear elasticity of the RBC membrane due to
the spectrin cytoskeleton, in addition to the membrane
bending rigidity. RBC membranes are modeled by
two-dimensional triangular networks of linked vertices,
which represent three-dimensional cell shapes. The phase
space of RBC doublet shapes in a wide range of adhesion
strengths, reduced volumes, and shear elasticities is
obtained. The shear elasticity of the RBC membrane changes
the doublet phases significantly. Experimental images of RBC
doublets in different solutions show similar configurations.
Furthermore, we show that rouleau formation is affected by
the doublet structure.},
cin = {ICS-2 / JARA-HPC},
ddc = {530},
cid = {I:(DE-Juel1)ICS-2-20110106 / $I:(DE-82)080012_20140620$},
pnm = {553 - Physical Basis of Diseases (POF3-553) / Formation of
Polymer-Particle Aggregates in Blood Flow
$(jiff44_20180501)$},
pid = {G:(DE-HGF)POF3-553 / $G:(DE-Juel1)jiff44_20180501$},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30014074},
UT = {WOS:000449199000012},
doi = {10.1039/C8SM00634B},
url = {https://juser.fz-juelich.de/record/850924},
}