Gast ::
| Hauptseite > Publikationsdatenbank > Association and Internal Morphology of Self-Assembled HPPhOx/BSA Hybrid Nanoparticles in Aqueous Solutions |
| Hauptseite > Publikationsdatenbank > Association and Internal Morphology of Self-Assembled HPPhOx/BSA Hybrid Nanoparticles in Aqueous Solutions |
| Journal Article | FZJ-2018-05116 |
; ; ;
2018
Soc.
Washington, DC
This record in other databases: 
Please use a persistent id in citations: doi:10.1021/acs.jpcb.8b04364
Abstract: We investigate the formation of hybrid polyelectrolyte/protein nanoparticles by associations between aggregates of partially hydrolyzed poly(2-phenyl-2-oxazoline) (HPPhOx) and bovine serum albumin (BSA) in aqueous solutions. Light scattering experiments show that at conditions of low salt, BSA creates interaggregate bridges and increases the size of the HPPhOx nanoparticles. At high salt contents, breaking of aggregates leads to well-defined nanoparticles. The interior of the formed nanoparticles is probed by small-angle neutron scattering. At low salt, diffuse arrangements are observed, whereas at high salt concentration, scattering is dominated by well-defined hydrophobic domains enhanced by the incorporation of BSA. This system shows that the combination of hydrophobic and electrostatic interactions in random-amphiphilic-polyelectrolyte/protein complexes can be used to determine the properties of self-assembled hybrid multifunctional nanoparticles.
Keyword(s): Polymers, Soft Nano Particles and Proteins (1st) ; Soft Condensed Matter (2nd)
; Current Contents - Physical, Chemical and Earth Sciences ; Ebsco Academic Search ; IF < 5 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection
|
The record appears in these collections: |
PDF
PDF (PDFA)