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000852741 0247_ $$2doi$$a10.1103/PhysRevLett.121.118103
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000852741 1001_ $$0P:(DE-Juel1)157877$$aMauer, Johannes$$b0
000852741 245__ $$aFlow-Induced Transitions of Red Blood Cell Shapes under Shears
000852741 260__ $$aCollege Park, Md.$$bAPS$$c2018
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000852741 520__ $$aA recent study of red blood cells (RBCs) in shear flow [Lanotte et al., Proc. Natl. Acad. Sci. U.S.A. 113, 13289 (2016)] has demonstrated that RBCs first tumble, then roll, transit to a rolling and tumbling stomatocyte, and finally attain polylobed shapes with increasing shear rate, when the viscosity contrast between cytosol and blood plasma is large enough. Using two different simulation techniques, we construct a state diagram of RBC shapes and dynamics in shear flow as a function of shear rate and viscosity contrast, which is also supported by microfluidic experiments. Furthermore, we illustrate the importance of RBC shear elasticity for its dynamics in flow and show that two different kinds of membrane buckling trigger the transition between subsequent RBC states.
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000852741 7001_ $$0P:(DE-HGF)0$$aMendez, Simon$$b1
000852741 7001_ $$0P:(DE-HGF)0$$aLanotte, Luca$$b2
000852741 7001_ $$0P:(DE-HGF)0$$aNicoud, Franck$$b3
000852741 7001_ $$0P:(DE-HGF)0$$aAbkarian, Manouk$$b4
000852741 7001_ $$0P:(DE-Juel1)130665$$aGompper, Gerhard$$b5
000852741 7001_ $$0P:(DE-HGF)0$$aFedosov, Dmitry A.$$b6$$eCorresponding author
000852741 773__ $$0PERI:(DE-600)1472655-5$$a10.1103/PhysRevLett.121.118103$$gVol. 121, no. 11, p. 118103$$n11$$p118103$$tPhysical review letters$$v121$$x1079-7114$$y2018
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