TY  - JOUR
AU  - Mauer, Johannes
AU  - Mendez, Simon
AU  - Lanotte, Luca
AU  - Nicoud, Franck
AU  - Abkarian, Manouk
AU  - Gompper, Gerhard
AU  - Fedosov, Dmitry A.
TI  - Flow-Induced Transitions of Red Blood Cell Shapes under Shears
JO  - Physical review letters
VL  - 121
IS  - 11
SN  - 1079-7114
CY  - College Park, Md.
PB  - APS
M1  - FZJ-2018-05613
SP  - 118103
PY  - 2018
AB  - A recent study of red blood cells (RBCs) in shear flow [Lanotte et al., Proc. Natl. Acad. Sci. U.S.A. 113, 13289 (2016)] has demonstrated that RBCs first tumble, then roll, transit to a rolling and tumbling stomatocyte, and finally attain polylobed shapes with increasing shear rate, when the viscosity contrast between cytosol and blood plasma is large enough. Using two different simulation techniques, we construct a state diagram of RBC shapes and dynamics in shear flow as a function of shear rate and viscosity contrast, which is also supported by microfluidic experiments. Furthermore, we illustrate the importance of RBC shear elasticity for its dynamics in flow and show that two different kinds of membrane buckling trigger the transition between subsequent RBC states.
LB  - PUB:(DE-HGF)16
C6  - pmid:30265089
UR  - <Go to ISI:>//WOS:000444586600022
DO  - DOI:10.1103/PhysRevLett.121.118103
UR  - https://juser.fz-juelich.de/record/852741
ER  -