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024 7 _ |a 10.1103/PhysRevLett.121.118103
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100 1 _ |a Mauer, Johannes
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245 _ _ |a Flow-Induced Transitions of Red Blood Cell Shapes under Shears
260 _ _ |a College Park, Md.
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520 _ _ |a A recent study of red blood cells (RBCs) in shear flow [Lanotte et al., Proc. Natl. Acad. Sci. U.S.A. 113, 13289 (2016)] has demonstrated that RBCs first tumble, then roll, transit to a rolling and tumbling stomatocyte, and finally attain polylobed shapes with increasing shear rate, when the viscosity contrast between cytosol and blood plasma is large enough. Using two different simulation techniques, we construct a state diagram of RBC shapes and dynamics in shear flow as a function of shear rate and viscosity contrast, which is also supported by microfluidic experiments. Furthermore, we illustrate the importance of RBC shear elasticity for its dynamics in flow and show that two different kinds of membrane buckling trigger the transition between subsequent RBC states.
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700 1 _ |a Mendez, Simon
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700 1 _ |a Lanotte, Luca
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700 1 _ |a Nicoud, Franck
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700 1 _ |a Abkarian, Manouk
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700 1 _ |a Gompper, Gerhard
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700 1 _ |a Fedosov, Dmitry A.
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773 _ _ |a 10.1103/PhysRevLett.121.118103
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