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000859245 1001_ $$0P:(DE-Juel1)130514$$aAuth, Thorsten$$b0$$eCorresponding author
000859245 245__ $$aInteraction of Particles and Pathogens with Biological Membranes
000859245 260__ $$aCham$$bSpringer International Publishing$$c2018
000859245 29510 $$aPhysics of Biological Membranes / Bassereau, Patricia (Editor)   ; Cham : Springer International Publishing, 2018, Chapter 17 ; ISBN: 978-3-030-00628-0 ; doi:10.1007/978-3-030-00630-3
000859245 300__ $$a471-498
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000859245 520__ $$aBiological membranes are both barriers and communication interfaces of cells. Transport across membranes is therefore essential for life. It encompasses both endocytotic and exocytotic processes important for cell function, but also the invasion of cells by parasites and viruses, and targeted drug delivery. Whereas interactions on the molecular scale are important for particles with sizes comparable with the thickness of the membrane, the mechanical properties of the entire membrane determine its interaction with larger particles. We focus here on large particles and parasites and discuss wrapping of single particles by homogeneous and complex membranes. Both solid particles with various shapes as well as soft particles are considered. Membrane-mediated interactions of many particles lead to aggregation and tubulation. Finally, active biological mechanisms are shown to support the invasion of parasites, such as the malaria parasite, and to drive phagocytosis.
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000859245 7001_ $$0P:(DE-Juel1)142341$$aDasgupta, Sabyasachi$$b1
000859245 7001_ $$0P:(DE-Juel1)130665$$aGompper, Gerhard$$b2
000859245 773__ $$a10.1007/978-3-030-00630-3_17
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000859245 9141_ $$y2018
000859245 9201_ $$0I:(DE-Juel1)ICS-2-20110106$$kICS-2$$lTheorie der Weichen Materie und Biophysik $$x0
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