%0 Journal Article
%A Hammes, Jochen
%A Hohberg, Melanie
%A Täger, Philipp
%A Wild, Markus
%A Zlatopolskiy, Boris
%A Krapf, Philipp
%A Neumaier, Bernd
%A Schomäcker, Klaus
%A Kobe, Carsten
%A Schmidt, Matthias
%A Dietlein, Markus
%A Drzezga, Alexander
%T Uptake in non-affected bone tissue does not differ between [18F]-DCFPyL and [68Ga]-HBED-CC PSMA PET/CT
%J PLOS ONE
%V 13
%N 12
%@ 1932-6203
%C San Francisco, California, US
%I PLOS
%M FZJ-2019-00145
%P e0209613 -
%D 2018
%X [68Ga]PSMA-HBED-CC and[18F]DCFPyL show a high potential for the detection of recurrent prostate cancer. While 18F-based tracers have several advantages in availability and image resolution, their sensitivity in the skeleton might be impaired by released [18F]fluoride due to its high bone affinity. In turn, chemically unbound trivalent 68Ga might also accumulate in osseous tissue, in cases of occupied binding sites of plasma proteins and thereby influence bone signal.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30571794
%U <Go to ISI:>//WOS:000453841700090
%R 10.1371/journal.pone.0209613
%U https://juser.fz-juelich.de/record/859273