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000861579 1001_ $$0P:(DE-Juel1)166459$$aGhosh Moulick, Ranjita$$b0$$eCorresponding author
000861579 245__ $$aPatterning artificial lipid bilayer on nanostructured surfaces
000861579 260__ $$aAuckland$$bDOVE Medical Press$$c2018
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000861579 520__ $$aArtificial lipid bilayer on solid substrate plays an important role as an interface between nanotechnology and biology. In this study, grid structures were patterned on Au-Nb-glass substrate and artificial bilayer was prepared on these structures. The fluidity was checked using fluorescence recovery after photobleaching (FRAP), and neuronal adhesion was monitored on such structure using EphrinA5-tethered lipid bilayer. EphrinA5 is a ligand that binds to the Eph receptors of rat cortical neurons and influences cellular adhesion. Our result elucidated that influence of these nanopatterned protein-tethered lipid bilayer on cellular guidance and signaling can address many underlying mechanisms of cellular functioning and help us to understand and differentiate the signaling procedure in cancer and neurodegenerative diseases.
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000861579 7001_ $$0P:(DE-Juel1)128715$$aPanaitov, Gregor$$b1
000861579 7001_ $$0P:(DE-Juel1)136888$$aChoi, Sung-Eun$$b2
000861579 7001_ $$0P:(DE-Juel1)128707$$aMayer, Dirk$$b3
000861579 7001_ $$0P:(DE-Juel1)128713$$aOffenhäusser, Andreas$$b4
000861579 773__ $$0PERI:(DE-600)2377464-2$$a10.2147/IJN.S125005$$gVol. Volume 13, p. 55 - 58$$p55 - 58$$tInternational journal of nanomedicine$$v 13$$x1178-2013$$y2018
000861579 8564_ $$uhttps://juser.fz-juelich.de/record/861579/files/IJN-125005-patterning-artificial-lipid-bilayer-on-nanostructured-surfac_031418.pdf$$yOpenAccess
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