Contribution to a conference proceedings FZJ-2019-02397

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ELASTIC REGISTRATION OF HIGH-RESOLUTION 3D PLI DATA OF THE HUMAN BRAIN

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2017

IEEE International Symposium on Biomedical Imaging, ISBI, BarcelonaBarcelona, Spain, 18 Apr 2017 - 21 Apr 20172017-04-182017-04-21 1-5 ()

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Abstract: We introduce a new approach for the elastic registration ofhigh-resolution 3D polarized light imaging (3D PLI) data ofhistological sections of the human brain. For accurate regis-tration of different types of 3D PLI modalities, we proposea novel intensity similarity measure that is based on a least-squares formulation of normalized cross-correlation. More-over, we present a fully automatic registration pipeline forrigid and elastic registration of high-resolution 3D PLI imageswith a blockface reference including a preprocessing step. Wehave successfully evaluated our approach using manually ob-tained ground truth for five sections of a human brain and ex-perimentally compared it with previous approaches. We alsopresent experimental results for 60 brain sections.


Contributing Institute(s):
  1. Strukturelle und funktionelle Organisation des Gehirns (INM-1)
Research Program(s):
  1. 571 - Connectivity and Activity (POF3-571) (POF3-571)
  2. HBP SGA1 - Human Brain Project Specific Grant Agreement 1 (720270) (720270)
  3. SMHB - Supercomputing and Modelling for the Human Brain (HGF-SMHB-2013-2017) (HGF-SMHB-2013-2017)

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 Record created 2019-04-02, last modified 2021-01-30