Home > Publications database > ELASTIC REGISTRATION OF HIGH-RESOLUTION 3D PLI DATA OF THE HUMAN BRAIN |
Contribution to a conference proceedings | FZJ-2019-02397 |
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2017
Please use a persistent id in citations: http://hdl.handle.net/2128/22221
Abstract: We introduce a new approach for the elastic registration ofhigh-resolution 3D polarized light imaging (3D PLI) data ofhistological sections of the human brain. For accurate regis-tration of different types of 3D PLI modalities, we proposea novel intensity similarity measure that is based on a least-squares formulation of normalized cross-correlation. More-over, we present a fully automatic registration pipeline forrigid and elastic registration of high-resolution 3D PLI imageswith a blockface reference including a preprocessing step. Wehave successfully evaluated our approach using manually ob-tained ground truth for five sections of a human brain and ex-perimentally compared it with previous approaches. We alsopresent experimental results for 60 brain sections.
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