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@ARTICLE{Ganai:863007,
      author       = {Ganai, Nirmalendu and Büscher, Tobias and Elgeti, Jens and
                      Gompper, Gerhard},
      title        = {{M}echanics of tissue competition: {I}nterfaces stabilize
                      coexistence},
      journal      = {New journal of physics},
      volume       = {21},
      issn         = {1367-2630},
      address      = {[London]},
      publisher    = {IOP73379},
      reportid     = {FZJ-2019-03153},
      pages        = {063017},
      year         = {2019},
      abstract     = {Mechanical forces influence the dynamics of growing
                      tissues. Computer simulations are employed to study the
                      importance of interfacial effects in tissue competition. It
                      was speculated previously that mechanical pressure
                      determines the competition, where the determining quantity
                      is the homeostatic pressure - the pressure where division
                      and apoptosis balance; the tissue with the higher
                      homeostatic pressure overwhelms the other. In contrast, we
                      find that a weaker tissue can persist in stable coexistence
                      with a stronger tissue, if adhesion between them is small
                      enough. An analytic continuum description can quantitatively
                      describe the underlying mechanism and reproduce the
                      resulting pressures and cell-number fractions. Furthermore,
                      simulations reveal a variety of coexisting structures,
                      ranging from spherical inclusions to a bicontinuous state.},
      cin          = {ICS-2},
      ddc          = {530},
      cid          = {I:(DE-Juel1)ICS-2-20110106},
      pnm          = {553 - Physical Basis of Diseases (POF3-553)},
      pid          = {G:(DE-HGF)POF3-553},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000471324900003},
      doi          = {10.1088/1367-2630/ab2475},
      url          = {https://juser.fz-juelich.de/record/863007},
}